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- References [16]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 18703-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18703-1-AP, RRID:AB_2084238
- Product name
- CPS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPS1 antibody (Cat. #18703-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions.
p53 inhibits the Urea cycle and represses polyamine biosynthesis in glioma cell lines.
Insight of a Metabolic Prognostic Model to Identify Tumor Environment and Drug Vulnerability for Lung Adenocarcinoma.
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Plasmodium sporozoite phospholipid scramblase interacts with mammalian carbamoyl-phosphate synthetase 1 to infect hepatocytes.
Serum proteome profiling provides a deep understanding of the 'gut-liver axis' in relation to liver injury and regeneration.
Therapeutic effect of N-carbamylglutamate in CPS1 deficiency.
Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite.
SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α.
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Caspase recruitment domain family member 10 regulates carbamoyl phosphate synthase 1 and promotes cancer growth in bladder cancer cells.
Studies on the biological functions of CPS1 in AFB1 induced hepatocarcinogenesis.
Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage.
Proteomics analysis of human nonalcoholic fatty liver.
Non-alcoholic fatty liver disease proteomics.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951
EMBO molecular medicine 2023 Jul 10;15(7):e16951
Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions.
Guo X, Liang K, Xia L, Zhang X, Liu J, Wang C, Li J, Li X, Hou X, Chen L
iScience 2023 Dec 15;26(12):108446
iScience 2023 Dec 15;26(12):108446
p53 inhibits the Urea cycle and represses polyamine biosynthesis in glioma cell lines.
Zhao Y, Chen Y, Wei L, Ran J, Wang K, Zhu S, Liu Q
Metabolic brain disease 2023 Apr;38(4):1143-1153
Metabolic brain disease 2023 Apr;38(4):1143-1153
Insight of a Metabolic Prognostic Model to Identify Tumor Environment and Drug Vulnerability for Lung Adenocarcinoma.
Peng SL, Wang R, Zhou YL, Wei W, Zhong GH, Huang XT, Yang S, Liu QD, Liu ZG
Frontiers in immunology 2022;13:872910
Frontiers in immunology 2022;13:872910
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Bai C, Wang H, Dong D, Li T, Yu Z, Guo J, Zhou W, Li D, Yan R, Wang L, Wang Z, Li Y, Ren L
Frontiers in cell and developmental biology 2021;9:650748
Frontiers in cell and developmental biology 2021;9:650748
Plasmodium sporozoite phospholipid scramblase interacts with mammalian carbamoyl-phosphate synthetase 1 to infect hepatocytes.
Cha SJ, Kim MS, Na CH, Jacobs-Lorena M
Nature communications 2021 Nov 19;12(1):6773
Nature communications 2021 Nov 19;12(1):6773
Serum proteome profiling provides a deep understanding of the 'gut-liver axis' in relation to liver injury and regeneration.
Leng L, Ma J, Lv L, Gao D, Li M, Wang Y, Zhu Y
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):372-380
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):372-380
Therapeutic effect of N-carbamylglutamate in CPS1 deficiency.
Sugiyama Y, Shimura M, Ogawa-Tominaga M, Ebihara T, Kinouchi Y, Isozaki K, Matsuhashi T, Tajika M, Fushimi T, Ichimoto K, Matsunaga A, Ishida T, Mizutani K, Tsuruoka T, Murayama K
Molecular genetics and metabolism reports 2020 Sep;24:100622
Molecular genetics and metabolism reports 2020 Sep;24:100622
Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite.
Ceccacci S, Deitersen J, Mozzicafreddo M, Morretta E, Proksch P, Wesselborg S, Stork B, Monti MC
Biomolecules 2020 Jun 2;10(6)
Biomolecules 2020 Jun 2;10(6)
SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α.
Zhang W, Dong Z, Xu M, Zhang S, Liu C, Chen S
Molecular metabolism 2020 Feb;32:85-96
Molecular metabolism 2020 Feb;32:85-96
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Cao Y, Ding W, Zhang J, Gao Q, Yang H, Cao W, Wang Z, Fang L, Du R
Journal of proteome research 2019 May 3;18(5):2032-2044
Journal of proteome research 2019 May 3;18(5):2032-2044
Caspase recruitment domain family member 10 regulates carbamoyl phosphate synthase 1 and promotes cancer growth in bladder cancer cells.
Liu X, Zhang X, Bi J, Li Z, Zhang Z, Kong C
Journal of cellular and molecular medicine 2019 Dec;23(12):8128-8138
Journal of cellular and molecular medicine 2019 Dec;23(12):8128-8138
Studies on the biological functions of CPS1 in AFB1 induced hepatocarcinogenesis.
Yang C, Fu R, Zhuang Z, Wang S
Gene 2016 Oct 10;591(1):255-261
Gene 2016 Oct 10;591(1):255-261
Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage.
Tummala KS, Gomes AL, Yilmaz M, Graña O, Bakiri L, Ruppen I, Ximénez-Embún P, Sheshappanavar V, Rodriguez-Justo M, Pisano DG, Wagner EF, Djouder N
Cancer cell 2014 Dec 8;26(6):826-839
Cancer cell 2014 Dec 8;26(6):826-839
Proteomics analysis of human nonalcoholic fatty liver.
Rodriguez-Suarez E, Mato JM, Elortza F
Methods in molecular biology (Clifton, N.J.) 2012;909:241-58
Methods in molecular biology (Clifton, N.J.) 2012;909:241-58
Non-alcoholic fatty liver disease proteomics.
Rodríguez-Suárez E, Duce AM, Caballería J, Martínez Arrieta F, Fernández E, Gómara C, Alkorta N, Ariz U, Martínez-Chantar ML, Lu SC, Elortza F, Mato JM
Proteomics. Clinical applications 2010 Apr;4(4):362-71
Proteomics. Clinical applications 2010 Apr;4(4):362-71
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 18703-1-AP(CPS1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CPS1 antibody 18703-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
