Antibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- ELISA [1]
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- Product number
- ABIN395260 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 658-758) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 658-758
- Isotype
- IgG
- Antibody clone number
- 2A11
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1.
Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA1 or BRCA2 breast cancer families.
BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.
A Large-scale genetic association study of esophageal adenocarcinoma risk.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Dizin E, Irminger-Finger I
The international journal of biochemistry & cell biology 2010 May;42(5):693-700
The international journal of biochemistry & cell biology 2010 May;42(5):693-700
Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA1 or BRCA2 breast cancer families.
De Brakeleer S, De Grève J, Loris R, Janin N, Lissens W, Sermijn E, Teugels E
Human mutation 2010 Mar;31(3):E1175-85
Human mutation 2010 Mar;31(3):E1175-85
BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.
Harte MT, O'Brien GJ, Ryan NM, Gorski JJ, Savage KI, Crawford NT, Mullan PB, Harkin DP
Cancer research 2010 Mar 15;70(6):2538-47
Cancer research 2010 Mar 15;70(6):2538-47
A Large-scale genetic association study of esophageal adenocarcinoma risk.
Liu CY, Wu MC, Chen F, Ter-Minassian M, Asomaning K, Zhai R, Wang Z, Su L, Heist RS, Kulke MH, Lin X, Liu G, Christiani DC
Carcinogenesis 2010 Jul;31(7):1259-63
Carcinogenesis 2010 Jul;31(7):1259-63
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
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