Tissue expression
Cell line expression
Protein structure
GSTM2
Glutathione S-transferase mu 2GST4
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Invitrogen Antibodies | 2946-MSM1-P0 | Monoclonal |
WB
ICC
IHC
FC
OA
|
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Novus Biologicals | H00002946-M03 | 1 references | Monoclonal |
WB
EL
ICC
IHC |
|
Abnova Corporation | H00002946-M03 | 1 references | Monoclonal |
WB
EL
ICC
IHC |
|
antibodies-online | ABIN516230 | 1 references | Monoclonal |
WB
EL
ICC
IHC |
|
LSBio | LS-B6092 | Monoclonal |
WB
EL
IHC
|
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Recommended by provider