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- Antibody Data
- Antigen structure
- References [28]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12412-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12412-1-AP, RRID:AB_2115925
- Product name
- GSTM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GSTM1 antibody (Cat. #12412-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Application of integrated omics in aseptic loosening of prostheses after hip replacement.
Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice.
The protective effects of active ingredients from acrorus tatarinowii on sperm and their molecular mechanisms.
Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy.
GSTT1/GSTM1 deficiency aggravated cisplatin-induced acute kidney injury via ROS-triggered ferroptosis.
A Natural Chalcone Cardamonin Inhibited Transformation of Aryl Hydrocarbon Receptor Through Binding to the Receptor Competitively.
Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain.
Deletion of IL-1β exacerbates acrylamide-induced neurotoxicity in mice.
Quantitative Proteomics Identifies Novel Nrf2-Mediated Adaptative Signaling Pathways in Skeletal Muscle Following Exercise Training.
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
Role of Nrf2 in 1,2-dichloropropane-induced cell proliferation and DNA damage in the mouse liver.
Glutathione S-transferases Control astrocyte activation and neuronal health during neuroinflammation.
Guanxin Xiaoban capsules could treat atherosclerosis by affecting the gut microbiome and inhibiting the AGE-RAGE signalling pathway.
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Gstm1/Gstt1 is essential for reducing cisplatin ototoxicity in CBA/CaJ mice.
Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection.
A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis.
Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy.
lncRNA-GM targets Foxo1 to promote T cell-mediated autoimmunity.
Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance.
Nrf2 expression in pancreatic stellate cells promotes progression of cancer.
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation.
A physiological concentration of luteolin induces phase II drug-metabolizing enzymes through the ERK1/2 signaling pathway in HepG2 cells.
Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.
Glutathione-S-transferases and Chemotherapy Resistance of Hodgkin's Lymphoma Cell Lines.
Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.
Liu YK, Dong YH, Liang XM, Qiang S, Li ME, Sun Z, Zhao X, Yan ZH, Zheng J
Molecular medicine reports 2025 Mar;31(3)
Molecular medicine reports 2025 Mar;31(3)
Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice.
Wang N, Li Y, Wang X, Yang L, Zhang J, Cheng J, Jiang X, Qi X, Wei C, Zhou Q, Li Y, Li S
Investigative ophthalmology & visual science 2025 Jun 2;66(6):28
Investigative ophthalmology & visual science 2025 Jun 2;66(6):28
The protective effects of active ingredients from acrorus tatarinowii on sperm and their molecular mechanisms.
Lu Z, Zhao H, Wang H, Wang X, Sun Z
Basic and clinical andrology 2025 Jan 20;35(1):2
Basic and clinical andrology 2025 Jan 20;35(1):2
Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy.
Xue C, Zhao S, Zhou Y, Chen Z, Liu J, Deng S, Zeng L, Zhao H, Xu Z, Li M, He X, Liu S, Liu S, Zhang S, Peng X, Wu X, Bai R, Zhuang L, Wu S, Zhang J, Lin D, Huang X, Zheng J
Cell metabolism 2025 Dec 2;37(12):2381-2401.e9
Cell metabolism 2025 Dec 2;37(12):2381-2401.e9
GSTT1/GSTM1 deficiency aggravated cisplatin-induced acute kidney injury via ROS-triggered ferroptosis.
Li P, Li D, Lu Y, Pan S, Cheng F, Li S, Zhang X, Huo J, Liu D, Liu Z
Frontiers in immunology 2024;15:1457230
Frontiers in immunology 2024;15:1457230
A Natural Chalcone Cardamonin Inhibited Transformation of Aryl Hydrocarbon Receptor Through Binding to the Receptor Competitively.
Zhang T, He C, Ota S, Kitakaze T, Yamaji R, Shimazu S, Yamashita Y, Ashida H
Molecular nutrition & food research 2024 Sep;68(18):e2400185
Molecular nutrition & food research 2024 Sep;68(18):e2400185
Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain.
Hamamoto K, Liang X, Ito A, Lanza M, Bui V, Zhang J, Opozda DM, Hattori T, Chen L, Haddock D, Imamura F, Wang HG, Takahashi Y
Cell reports 2024 Dec 24;43(12):115016
Cell reports 2024 Dec 24;43(12):115016
Deletion of IL-1β exacerbates acrylamide-induced neurotoxicity in mice.
Fergany A, Zong C, Ekuban FA, Suzuki A, Kimura Y, Ichihara S, Iwakura Y, Ichihara G
Toxicological sciences : an official journal of the Society of Toxicology 2023 Sep 28;195(2):246-256
Toxicological sciences : an official journal of the Society of Toxicology 2023 Sep 28;195(2):246-256
Quantitative Proteomics Identifies Novel Nrf2-Mediated Adaptative Signaling Pathways in Skeletal Muscle Following Exercise Training.
Bhat A, Abu R, Jagadesan S, Vellichirammal NN, Pendyala VV, Yu L, Rudebush TL, Guda C, Zucker IH, Kumar V, Gao L
Antioxidants (Basel, Switzerland) 2023 Jan 9;12(1)
Antioxidants (Basel, Switzerland) 2023 Jan 9;12(1)
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
Zhang W, Dai J, Hou G, Liu H, Zheng S, Wang X, Lin Q, Zhang Y, Lu M, Gong Y, Xiang Z, Yu Y, Hu Y
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
Role of Nrf2 in 1,2-dichloropropane-induced cell proliferation and DNA damage in the mouse liver.
Kimura Y, Ekuban FA, Zong C, Sugie S, Zhang X, Itoh K, Yamamoto M, Ichihara S, Ohsako S, Ichihara G
Toxicological sciences : an official journal of the Society of Toxicology 2023 Aug 29;195(1):28-41
Toxicological sciences : an official journal of the Society of Toxicology 2023 Aug 29;195(1):28-41
Glutathione S-transferases Control astrocyte activation and neuronal health during neuroinflammation.
Matoba K, Dohi E, Choi EY, Kano SI
Frontiers in molecular biosciences 2022;9:1080140
Frontiers in molecular biosciences 2022;9:1080140
Guanxin Xiaoban capsules could treat atherosclerosis by affecting the gut microbiome and inhibiting the AGE-RAGE signalling pathway.
Dongliang Y, Yang R, Peng S, Deng J, Huo Y, Deng Z, Yau Y, Liu J, Liao D, Cheng C
Journal of medical microbiology 2022 May;71(5)
Journal of medical microbiology 2022 May;71(5)
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Zhang H, Wu J, Li Y, Jin G, Tian Y, Kang S
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1630-1643
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1630-1643
Gstm1/Gstt1 is essential for reducing cisplatin ototoxicity in CBA/CaJ mice.
Li P, Liu Z, Wang J, Bi X, Xiao Y, Qiao R, Zhou X, Guo S, Wan P, Chang M, Hong G, Liu Z, Ming X, Gao J, Fu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22373
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22373
Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection.
Song Y, Shou S, Guo H, Gao Z, Liu N, Yang Y, Wang F, Deng Q, Liu J, Xie Y
Virologica Sinica 2022 Aug;37(4):558-568
Virologica Sinica 2022 Aug;37(4):558-568
A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis.
Lee E, Jung YJ, Park YR, Lim S, Choi YJ, Lee SY, Kim CH, Mun JY, Chung WS
Nature aging 2022 Aug;2(8):726-741
Nature aging 2022 Aug;2(8):726-741
Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy.
Berdowski WM, van der Linde HC, Breur M, Oosterhof N, Beerepoot S, Sanderson L, Wijnands LI, de Jong P, Tsai-Meu-Chong E, de Valk W, de Witte M, van IJcken WFJ, Demmers J, van der Knaap MS, Bugiani M, Wolf NI, van Ham TJ
Acta neuropathologica 2022 Aug;144(2):211-239
Acta neuropathologica 2022 Aug;144(2):211-239
lncRNA-GM targets Foxo1 to promote T cell-mediated autoimmunity.
Chen Y, Liu J, Zhang X, Zhu H, Wang Y, Li Z, Liu Y, Liu S, Liu S, Li N, Chen K, Cao X
Science advances 2022 Aug 5;8(31):eabn9181
Science advances 2022 Aug 5;8(31):eabn9181
Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance.
Yue R, Chen GY, Xie G, Hao L, Guo W, Sun X, Jia W, Zhang Q, Zhou Z, Zhong W
Free radical biology & medicine 2021 Oct;174:249-263
Free radical biology & medicine 2021 Oct;174:249-263
Nrf2 expression in pancreatic stellate cells promotes progression of cancer.
Tanaka Y, Hamada S, Matsumoto R, Taguchi K, Yamamoto M, Masamune A
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G378-G388
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G378-G388
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
Dai JM, Guo WN, Tan YZ, Niu KW, Zhang JJ, Liu CL, Yang XM, Tao KS, Chen ZN, Dai JY
Journal of cellular and molecular medicine 2021 Jun;25(12):5782-5798
Journal of cellular and molecular medicine 2021 Jun;25(12):5782-5798
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Deng Z, Lim J, Wang Q, Purtell K, Wu S, Palomo GM, Tan H, Manfredi G, Zhao Y, Peng J, Hu B, Chen S, Yue Z
Autophagy 2020 May;16(5):917-931
Autophagy 2020 May;16(5):917-931
Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation.
Wang Y, Wang P, Zhang Y, Xu J, Li Z, Li Z, Zhou Z, Liu L, Cao X
Immunity 2020 Dec 15;53(6):1168-1181.e7
Immunity 2020 Dec 15;53(6):1168-1181.e7
A physiological concentration of luteolin induces phase II drug-metabolizing enzymes through the ERK1/2 signaling pathway in HepG2 cells.
Kitakaze T, Makiyama A, Samukawa Y, Jiang S, Yamashita Y, Ashida H
Archives of biochemistry and biophysics 2019 Mar 15;663:151-159
Archives of biochemistry and biophysics 2019 Mar 15;663:151-159
Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.
Kano SI, Choi EY, Dohi E, Agarwal S, Chang DJ, Wilson AM, Lo BD, Rose IVL, Gonzalez S, Imai T, Sawa A
Science signaling 2019 Feb 19;12(569)
Science signaling 2019 Feb 19;12(569)
Glutathione-S-transferases and Chemotherapy Resistance of Hodgkin's Lymphoma Cell Lines.
Bernig T, Ritz S, Brodt G, Volkmer I, Staege MS
Anticancer research 2016 Aug;36(8):3905-15
Anticancer research 2016 Aug;36(8):3905-15
Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.
Shirai M, Arakawa S, Miida H, Matsuyama T, Kinoshita J, Makino T, Kai K, Teranishi M
Journal of toxicologic pathology 2013 Jun;26(2):175-86
Journal of toxicologic pathology 2013 Jun;26(2):175-86
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse ovary tissue were subjected to SDS PAGE followed by western blot with 12412-1-AP(GSTM1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GSTM1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GSTM1. This antibody recognizes human, mouse antigen. The GSTM1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
