DPAB0538

antibody from Creative Diagnostics

Targeting: GSTM1 GST1, H-B, MU

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DPAB0538

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPAB0538, RRID:AB_2345109

Product name

Rabbit anti-Glutathione-S-Transferase Polyclonal antibody

Antibody type

Polyclonal

Description

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Enzymes of the glutathione S-transferase (GST) family are composed of many cytosolic, mitochondrial, and microsomal (now designated as MAPEG) proteins. GSTs are present in eukaryotes and in prokaryotes, where they catalyze a variety of reactions and accept endogenous and xenobiotic substrates. GSTs can constitute up to 10% of cytosolic protein in some mammalian organs. GSTs catalyse the conjugation of reduced glutathione ¨• via a sulfhydryl group ¨• to electrophilic centers on a wide variety of substrates. This activity detoxifies endogenous compounds such as peroxidised lipids, as well as breakdown of xenobiotics. GSTs may also bind toxins and function as transport proteins, and, therefore, an early term for GSTs was "ligandin". The mammalian GST super-family consists of cytosolic dimeric isoenzymes of 45ÿ55 kDa size that have been assigned to at least six classes: Alpha, Mu, Pi, Theta, Zeta and Omega

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Concentration

1mg/ml (OD280nm, E0.1% = 1.4)

Storage

Store at 2-8°C.