Tissue expression
Cell line expression
Protein structure
ASPN
AsporinFLJ20129, PLAP-1, SLRR1C
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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Acris Antibodies GmbH | ![]() |
Polyclonal |
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