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Protein structure
CHRND
Cholinergic receptor nicotinic delta subunitACHRD
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Top validated antibodies |
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| Novus Biologicals |  NB120-2804 |
5 references | Monoclonal |
WB
ICC
IP
IHC
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| GeneTex | GTX22804 |
Monoclonal |
WB
EL
ICC
IP
IHC
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| antibodies-online | ABIN266941 |
3 references | Monoclonal |
WB
ICC
IP
IHC
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| Invitrogen Antibodies | MA5-31696 |
Monoclonal |
WB
EL
FC
|
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| NovoPro Bioscience Inc. | 134929 |
Polyclonal |
WB
EL
FC
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