HPA018142

antibody from Atlas Antibodies

Targeting: SETDB1 ESET, KG1T, KIAA0067, KMT1E, TDRD21

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA018142

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA018142, RRID:AB_1856757

Product name

Anti-SETDB1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human SETDB1, Gene description: SET domain, bifurcated 1, Alternative Gene Names: ESET, KG1T, KIAA0067, KMT1E, TDRD21, Validated applications: IHC, ICC, Uniprot ID: Q15047, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma

Yang W, Wei Y, Wang T, Xu Y, Jin X, Qian H, Yang S, He S
International Journal of Molecular Medicine 2024;53(4)

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RETRACTED ARTICLE: SETDB1 promotes glioblastoma growth via CSF-1-dependent macrophage recruitment by activating the AKT/mTOR signaling pathway

Han S, Zhen W, Guo T, Zou J, Li F
Journal of Experimental & Clinical Cancer Research 2020;39(1)

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A regulatory circuitry comprising TP53, miR-29 family, and SETDB1 in non-small cell lung cancer

Chen B, Wang J, Wang J, Wang H, Gu X, Tang L, Feng X
Bioscience Reports 2018;38(5)

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Smad3‐mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial–mesenchymal transition

Du D, Katsuno Y, Meyer D, Budi E, Chen S, Koeppen H, Wang H, Akhurst R, Derynck R
EMBO reports 2017;19(1):135-155

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SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway

Sun Q, Ding L, Xiao J, Chien W, Lim S, Hattori N, Goodglick L, Chia D, Mah V, Alavi M, Kim S, Doan N, Said J, Loh X, Xu L, Liu L, Yang H, Hayano T, Shi S, Xie D, Lin D, Koeffler H
The Journal of Pathology 2015;235(4):559-570

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Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

Rodriguez-Paredes M, Martinez de Paz A, Simó-Riudalbas L, Sayols S, Moutinho C, Moran S, Villanueva A, Vázquez-Cedeira M, Lazo P, Carneiro F, Moura C, Vieira J, Teixeira M, Esteller M
Oncogene 2013;33(21):2807-2813

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The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

Ceol C, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando D, Battisti V, Fritsch L, Lin W, Hollmann T, Ferré F, Bourque C, Burke C, Turner L, Uong A, Johnson L, Beroukhim R, Mermel C, Loda M, Ait-Si-Ali S, Garraway L, Young R, Zon L
Nature 2011;471(7339):513-517