Tissue expression
Cell line expression
Protein structure
SETDB1
SET domain bifurcated histone lysine methyltransferase 1ESET, KG1T, KIAA0067, KMT1E, TDRD21
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jun 2011]
Top validated antibodies |
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| Proteintech Group | 77 references | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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| antibodies-online | 5 references | Monoclonal |
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| GeneTex | 2 references | Polyclonal |
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