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- Product number
- 18106-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18106-1-AP, RRID:AB_10732952
- Product name
- PD-1/CD279 antibody
- Antibody type
- Polyclonal
- Description
- PD-1/CD279 antibody (Cat. #18106-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Construction of disulfidptosis-based immune response prediction model with artificial intelligence and validation of the pivotal grouping oncogene c-MET in regulating T cell exhaustion.
Radiotherapy upregulated immune checkpoints contribute to the development of second primary OSCC.
The development and characterization of a CRISPR/Cas9-mediated PD-1 functional knockout rat as a tool to study idiosyncratic drug reactions.
Expression levels of key immune indicators and immune checkpoints in manganese-exposed rats.
Delta-tocotrienol disrupts PD-L1 glycosylation and reverses PD-L1-mediated immune suppression.
The regulation of the PD-1/PD-L1 pathway in imiquimod-induced chronic psoriasis itch and itch sensitization in mouse.
LRP5 competes for SPOP binding to enhance tumorigenesis mediated by Daxx and PD-L1 in prostate cancer.
Anti-PD-1 treatment protects against seizure by suppressing sodium channel function.
Safflower Yellow Inhibits Progression of Hepatocellular Carcinoma by Modulating Immunological Tolerance via FAK Pathway.
Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.
Targeting PD-1/PD-L1 inhibits rejection in a heterotopic tracheal allograft model of lung transplantation.
Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrate.
TANK shapes an immunosuppressive microenvironment and predicts prognosis and therapeutic response in glioma.
Engineered Cytokine-Primed Extracellular Vesicles with High PD-L1 Expression Ameliorate Type 1 Diabetes.
Electroacupuncture alleviates neuropathic pain caused by SNL by promoting M2 microglia polarization through PD-L1.
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Exploration of (68)Ga-labelled prostate-specific membrane antigen-11 PET/CT parameters for identifying PBRM1 status in primary clear cell renal cell carcinoma.
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
PD-1(+) mast cell enhanced by PD-1 blocking therapy associated with resistance to immunotherapy.
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
A nanotherapeutic system for gastric cancer suppression by synergistic chemotherapy and immunotherapy based on iPSCs and DCs exosomes.
GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer.
The antitumour effects of caloric restriction are mediated by the gut microbiome.
PD-1/PD-L1 blockade is a potent adjuvant in treatment of Staphylococcus aureus osteomyelitis in mice.
Docosahexaenoic acid reverses PD-L1-mediated immune suppression by accelerating its ubiquitin-proteasome degradation.
GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer.
Tumor Cell-Derived Microparticles Induced by Methotrexate Augment T-cell Antitumor Responses by Downregulating Expression of PD-1 in Neutrophils.
A novel immune score model predicting the prognosis and immunotherapy response of breast cancer.
Interaction of immune checkpoint PD-1 and chemokine receptor 4 (CXCR4) promotes a malignant phenotype in pancreatic cancer cells.
Signature construction and molecular subtype identification based on cuproptosis-related genes to predict the prognosis and immune activity of patients with hepatocellular carcinoma.
Identification of ST3GAL5 as a prognostic biomarker correlating with CD8(+) T cell exhaustion in clear cell renal cell carcinoma.
Bifidobacterium infantis Promotes Foxp3 Expression in Colon Cells via PD-L1-Mediated Inhibition of the PI3K-Akt-mTOR Signaling Pathway.
Polyglutamate-based nanoconjugates for image-guided surgery and post-operative melanoma metastases prevention.
Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients with low-grade glioma.
The immune checkpoint expression in the tumor immune microenvironment of DLBCL: Clinicopathologic features and prognosis.
PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.
Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma.
Traditional Chinese medicine CFF-1 exerts a potent anti-tumor immunity to hinder tumor growth and metastasis in prostate cancer through EGFR/JAK1/STAT3 pathway to inhibit PD-1/PD-L1 checkpoint signaling.
Immunotherapy landscape analyses of necroptosis characteristics for breast cancer patients.
Bifidobacterium infantis regulates the programmed cell death 1 pathway and immune response in mice with inflammatory bowel disease.
Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway.
Extracellular vesicles produced by bone marrow mesenchymal stem cells overexpressing programmed death-ligand 1 ameliorate dextran sodium sulfate-induced ulcerative colitis in rats by regulating Th17/Treg cell balance through PTEN/PI3K/AKT/mTOR axis.
Association of MARCH7 with tumor progression and T-cell infiltration in esophageal cancer.
Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy.
Inhibition of PD-L1-mediated tumor-promoting signaling is involved in the anti-cancer activity of β-tocotrienol.
Involvement of PD-L1-mediated tumor-intrinsic signaling and immune suppression in tumorigenic effect of α-tocopherol.
Methylation and Expression of the Exercise-Related TLR1 Gene Is Associated With Low Grade Glioma Prognosis and Outcome.
Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice.
TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma.
Clinical significance of sarcoid-like reaction in lymph nodes of gastric cancer patients.
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
The PD-1/PD-L1 pathway in murine hair cycle transition: a potential anagen phase regulator.
Altered peripheral helper T cells in peripheral blood and muscle tissue of the patients with dermatomyositis.
PD-1/PD-L1 enhanced cisplatin resistance in gastric cancer through PI3K/AKT mediated P-gp expression.
Relationship between PD-L1 expression, CD8+ T-cell infiltration and prognosis in intrahepatic cholangiocarcinoma patients.
Nutritional supplements in combination with chemotherapy or targeted therapy reduces tumor progression in mice bearing triple-negative breast cancer.
Antifibrotic effect of Gancao Ganjiang decoction is mediated by PD-1 / TGF-β1 / IL-17A pathway in bleomycin-induced idiopathic pulmonary fibrosis.
Intratumoral administration of the Toll-like receptor 7/8 agonist 3M-052 enhances interferon-driven tumor immunogenicity and suppresses metastatic spread in preclinical triple-negative breast cancer.
BTLA Expression in Stage I-III Non-Small-Cell Lung Cancer and Its Correlation with PD-1/PD-L1 and Clinical Outcomes.
Isolation of DNA Aptamer Targeting PD-1 with an Antitumor Immunotherapy Effect.
Synergistic anti-liver cancer effects of curcumin and total ginsenosides.
Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.
New insight on the correlation of metabolic status on (18)F-FDG PET/CT with immune marker expression in patients with non-small cell lung cancer.
Programmed Cell Death-1: Programmed Cell Death-Ligand 1 Interaction Protects Human Cardiomyocytes Against T-Cell Mediated Inflammation and Apoptosis Response In Vitro.
Molecular subtyping reveals immune alterations in IDH wild-type lower-grade diffuse glioma.
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
Efficient Gene Silencing by Adenine Base Editor-Mediated Start Codon Mutation.
Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC.
Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease.
Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer.
Expression of PD-1/PD-L1 in head and neck squamous cell carcinoma and its clinical significance.
Estradiol Attenuates the Severity of Primary Toxoplasma gondii Infection-Induced Adverse Pregnancy Outcomes Through the Regulation of Tregs in a Dose-Dependent Manner.
PD-1/PD-L1 Axis, Rather Than High-Mobility Group Alarmins or CD8+ Tumor-Infiltrating Lymphocytes, Is Associated With Survival in Head and Neck Squamous Cell Carcinoma Patients Who Received Surgical Resection.
Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma.
Immunological markers predict the prognosis of patients with squamous non-small cell lung cancer.
Li P, Wang S, Wan H, Huang Y, Yin K, Sun K, Jin H, Wang Z
Frontiers in immunology 2024;15:1258475
Frontiers in immunology 2024;15:1258475
Radiotherapy upregulated immune checkpoints contribute to the development of second primary OSCC.
Wang L, Wang S, Zhang J, Peng J, Cheng B, Li H, Hu Q
Oral diseases 2024 May;30(4):2188-2201
Oral diseases 2024 May;30(4):2188-2201
The development and characterization of a CRISPR/Cas9-mediated PD-1 functional knockout rat as a tool to study idiosyncratic drug reactions.
Cho T, Wierk A, Gertsenstein M, Rodgers CE, Uetrecht J, Henderson JT
Toxicological sciences : an official journal of the Society of Toxicology 2024 Mar 26;198(2):233-245
Toxicological sciences : an official journal of the Society of Toxicology 2024 Mar 26;198(2):233-245
Expression levels of key immune indicators and immune checkpoints in manganese-exposed rats.
Qi Y, Si H, Jin X, Guo Y, Xia J, He J, Deng X, Deng M, Yao W, Hao C
Ecotoxicology and environmental safety 2024 Mar 1;272:116029
Ecotoxicology and environmental safety 2024 Mar 1;272:116029
Delta-tocotrienol disrupts PD-L1 glycosylation and reverses PD-L1-mediated immune suppression.
Sun Z, Ma X, Zhao C, Fan L, Yin S, Hu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116078
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116078
The regulation of the PD-1/PD-L1 pathway in imiquimod-induced chronic psoriasis itch and itch sensitization in mouse.
Xu Z, Wang Y, Jiang C, Wang Z, Cheng Y, Fan M
Molecular pain 2024 Jan-Dec;20:17448069241252384
Molecular pain 2024 Jan-Dec;20:17448069241252384
LRP5 competes for SPOP binding to enhance tumorigenesis mediated by Daxx and PD-L1 in prostate cancer.
Gan S, Qu F, Zhang X, Pan X, Xu D, Cui X, Hou J
Experimental cell research 2024 Jan 1;434(1):113857
Experimental cell research 2024 Jan 1;434(1):113857
Anti-PD-1 treatment protects against seizure by suppressing sodium channel function.
Yang Y, Chen Z, Zhou J, Jiang S, Wang G, Wan L, Yu J, Jiang M, Wang Y, Hu J, Liu X, Wang Y
CNS neuroscience & therapeutics 2024 Apr;30(4):e14504
CNS neuroscience & therapeutics 2024 Apr;30(4):e14504
Safflower Yellow Inhibits Progression of Hepatocellular Carcinoma by Modulating Immunological Tolerance via FAK Pathway.
Ji HF, Yang ZQ, Han JJ, Li HF, Jin ZQ, Chen WQ, Chen FH, Gong MC
Chinese journal of integrative medicine 2024 Apr;30(4):339-347
Chinese journal of integrative medicine 2024 Apr;30(4):339-347
Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.
Xu C, Cheng S, Chen K, Song Q, Liu C, Fan C, Zhang R, Zhu Q, Wu Z, Wang Y, Fan J, Zheng H, Lu L, Chen T, Zhao H, Jiao Y, Qu C
Cellular and molecular gastroenterology and hepatology 2023;15(2):327-354
Cellular and molecular gastroenterology and hepatology 2023;15(2):327-354
Targeting PD-1/PD-L1 inhibits rejection in a heterotopic tracheal allograft model of lung transplantation.
Kaiho T, Suzuki H, Hata A, Matsumoto H, Tanaka K, Sakairi Y, Motohashi S, Yoshino I
Frontiers in pharmacology 2023;14:1298085
Frontiers in pharmacology 2023;14:1298085
Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrate.
Liu K, Chen J, Zhao Y, Boland J, Ting KK, Lockwood G, McKenzie C, Kench J, Vadas MA, Gamble JR, McCaughan GW
Frontiers in immunology 2023;14:1245708
Frontiers in immunology 2023;14:1245708
TANK shapes an immunosuppressive microenvironment and predicts prognosis and therapeutic response in glioma.
Li S, Guo Y, Hu H, Gao N, Yan X, Zhou Q, Liu H
Frontiers in immunology 2023;14:1138203
Frontiers in immunology 2023;14:1138203
Engineered Cytokine-Primed Extracellular Vesicles with High PD-L1 Expression Ameliorate Type 1 Diabetes.
Wang L, Qi C, Cao H, Zhang Y, Liu X, Qiu L, Wang H, Xu L, Wu Z, Liu J, Wang S, Kong D, Wang Y
Small (Weinheim an der Bergstrasse, Germany) 2023 Sep;19(38):e2301019
Small (Weinheim an der Bergstrasse, Germany) 2023 Sep;19(38):e2301019
Electroacupuncture alleviates neuropathic pain caused by SNL by promoting M2 microglia polarization through PD-L1.
Wu Q, Zheng Y, Yu J, Ying X, Gu X, Tan Q, Tu W, Lou X, Yang G, Li M, Jiang S
International immunopharmacology 2023 Oct;123:110764
International immunopharmacology 2023 Oct;123:110764
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Yang L, Zhao Q, Chen T, Liu W, Qiu X, Chen J, Huang S, Huang R, Dong L
Clinical and experimental medicine 2023 Nov;23(7):3767-3780
Clinical and experimental medicine 2023 Nov;23(7):3767-3780
Exploration of (68)Ga-labelled prostate-specific membrane antigen-11 PET/CT parameters for identifying PBRM1 status in primary clear cell renal cell carcinoma.
Wang B, Deng Y, Xu Q, Gao J, Shen H, He X, Ding Q, Wang F, Guo H
Clinical radiology 2023 May;78(5):e417-e424
Clinical radiology 2023 May;78(5):e417-e424
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.
Bhin J, Paes Dias M, Gogola E, Rolfs F, Piersma SR, de Bruijn R, de Ruiter JR, van den Broek B, Duarte AA, Sol W, van der Heijden I, Andronikou C, Kaiponen TS, Bakker L, Lieftink C, Morris B, Beijersbergen RL, van de Ven M, Jimenez CR, Wessels LFA, Rottenberg S, Jonkers J
Cell reports 2023 May 30;42(5):112538
Cell reports 2023 May 30;42(5):112538
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Xiao X, Shi J, He C, Bu X, Sun Y, Gao M, Xiang B, Xiong W, Dai P, Mao Q, Xing X, Yao Y, Yu H, Xu G, Li S, Ren Y, Chen B, Jiang C, Meng G, Lee YR, Wei W, Freeman GJ, Xie C, Zhang J
Nature communications 2023 May 19;14(1):2859
Nature communications 2023 May 19;14(1):2859
PD-1(+) mast cell enhanced by PD-1 blocking therapy associated with resistance to immunotherapy.
Li J, Peng G, Zhu K, Jie X, Xu Y, Rao X, Xu Y, Chen Y, Xing B, Wu G, Shi L
Cancer immunology, immunotherapy : CII 2023 Mar;72(3):633-645
Cancer immunology, immunotherapy : CII 2023 Mar;72(3):633-645
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
Ye S, Li S, Qin L, Zheng W, Liu B, Li X, Ren Z, Zhao H, Hu X, Ye N, Li G
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
A nanotherapeutic system for gastric cancer suppression by synergistic chemotherapy and immunotherapy based on iPSCs and DCs exosomes.
Li Y, Tian L, Zhao T, Zhang J
Cancer immunology, immunotherapy : CII 2023 Jun;72(6):1673-1683
Cancer immunology, immunotherapy : CII 2023 Jun;72(6):1673-1683
GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer.
Huntington KE, Louie AD, Srinivasan PR, Schorl C, Lu S, Silverberg D, Newhouse D, Wu Z, Zhou L, Borden BA, Giles FJ, Dooner M, Carneiro BA, El-Deiry WS
International journal of molecular sciences 2023 Jun 29;24(13)
International journal of molecular sciences 2023 Jun 29;24(13)
The antitumour effects of caloric restriction are mediated by the gut microbiome.
Mao YQ, Huang JT, Zhang SL, Kong C, Li ZM, Jing H, Chen HL, Kong CY, Huang SH, Cai PR, Han B, Wang LS
Nature metabolism 2023 Jan;5(1):96-110
Nature metabolism 2023 Jan;5(1):96-110
PD-1/PD-L1 blockade is a potent adjuvant in treatment of Staphylococcus aureus osteomyelitis in mice.
Li K, Chen Y, Lin Y, Zhang G, Su J, Wu X, Cheng C, Wang Y, Yu B, Zhang X
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jan 4;31(1):174-192
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jan 4;31(1):174-192
Docosahexaenoic acid reverses PD-L1-mediated immune suppression by accelerating its ubiquitin-proteasome degradation.
Zhang H, Chen H, Yin S, Fan L, Jin C, Zhao C, Hu H
The Journal of nutritional biochemistry 2023 Feb;112:109186
The Journal of nutritional biochemistry 2023 Feb;112:109186
GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer.
Huntington KE, Louie AD, Srinivasan PR, Schorl C, Lu S, Silverberg D, Newhouse D, Wu Z, Zhou L, Borden BA, Giles FJ, Dooner M, Carneiro BA, El-Deiry WS
bioRxiv : the preprint server for biology 2023 Feb 7;
bioRxiv : the preprint server for biology 2023 Feb 7;
Tumor Cell-Derived Microparticles Induced by Methotrexate Augment T-cell Antitumor Responses by Downregulating Expression of PD-1 in Neutrophils.
Xu P, Zhang X, Chen K, Zhu M, Jia R, Zhou Q, Yang J, Dai J, Jin Y, Shi K
Cancer immunology research 2023 Apr 3;11(4):501-514
Cancer immunology research 2023 Apr 3;11(4):501-514
A novel immune score model predicting the prognosis and immunotherapy response of breast cancer.
Lv W, He X, Wang Y, Zhao C, Dong M, Wu Y, Zhang Q
Scientific reports 2023 Apr 19;13(1):6403
Scientific reports 2023 Apr 19;13(1):6403
Interaction of immune checkpoint PD-1 and chemokine receptor 4 (CXCR4) promotes a malignant phenotype in pancreatic cancer cells.
Harper MM, Lin M, Cavnar MJ, Pandalai PK, Patel RA, Gao M, Kim J
PloS one 2022;17(7):e0270832
PloS one 2022;17(7):e0270832
Signature construction and molecular subtype identification based on cuproptosis-related genes to predict the prognosis and immune activity of patients with hepatocellular carcinoma.
Peng X, Zhu J, Liu S, Luo C, Wu X, Liu Z, Li Y, Yuan R
Frontiers in immunology 2022;13:990790
Frontiers in immunology 2022;13:990790
Identification of ST3GAL5 as a prognostic biomarker correlating with CD8(+) T cell exhaustion in clear cell renal cell carcinoma.
Liu J, Li M, Wu J, Qi Q, Li Y, Wang S, Liang S, Zhang Y, Zhu Z, Huang R, Yan J, Zhu R
Frontiers in immunology 2022;13:979605
Frontiers in immunology 2022;13:979605
Bifidobacterium infantis Promotes Foxp3 Expression in Colon Cells via PD-L1-Mediated Inhibition of the PI3K-Akt-mTOR Signaling Pathway.
Zhou L, Xie Y, Li Y
Frontiers in immunology 2022;13:871705
Frontiers in immunology 2022;13:871705
Polyglutamate-based nanoconjugates for image-guided surgery and post-operative melanoma metastases prevention.
Epshtein Y, Blau R, Pisarevsky E, Koshrovski-Michael S, Ben-Shushan D, Pozzi S, Shenbach-Koltin G, Fridrich L, Buzhor M, Krivitsky A, Dey P, Satchi-Fainaro R
Theranostics 2022;12(14):6339-6362
Theranostics 2022;12(14):6339-6362
Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients with low-grade glioma.
Zhang N, Zhang H, Wu W, Zhou R, Li S, Wang Z, Dai Z, Zhang L, Liu F, Liu Z, Zhang J, Luo P, Liu Z, Cheng Q
Theranostics 2022;12(13):5931-5948
Theranostics 2022;12(13):5931-5948
The immune checkpoint expression in the tumor immune microenvironment of DLBCL: Clinicopathologic features and prognosis.
Ma J, Pang X, Li J, Zhang W, Cui W
Frontiers in oncology 2022;12:1069378
Frontiers in oncology 2022;12:1069378
PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.
Zhang H, Wang Y, Zhao Y, Liu T, Wang Z, Zhang N, Dai Z, Wu W, Cao H, Feng S, Zhang L, Cheng Q, Liu Z
CNS neuroscience & therapeutics 2022 Nov;28(11):1748-1766
CNS neuroscience & therapeutics 2022 Nov;28(11):1748-1766
Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma.
Zhang H, Zhang N, Wu W, Zhou R, Li S, Wang Z, Dai Z, Zhang L, Liu Z, Zhang J, Luo P, Liu Z, Cheng Q
Briefings in bioinformatics 2022 Nov 19;23(6)
Briefings in bioinformatics 2022 Nov 19;23(6)
Traditional Chinese medicine CFF-1 exerts a potent anti-tumor immunity to hinder tumor growth and metastasis in prostate cancer through EGFR/JAK1/STAT3 pathway to inhibit PD-1/PD-L1 checkpoint signaling.
Zhang Y, Wei Y, Jiang S, Dang Y, Yang Y, Zuo W, Zhu Q, Liu P, Gao Y, Lu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153939
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153939
Immunotherapy landscape analyses of necroptosis characteristics for breast cancer patients.
Yu H, Lv W, Tan Y, He X, Wu Y, Wu M, Zhang Q
Journal of translational medicine 2022 Jul 21;20(1):328
Journal of translational medicine 2022 Jul 21;20(1):328
Bifidobacterium infantis regulates the programmed cell death 1 pathway and immune response in mice with inflammatory bowel disease.
Zhou LY, Xie Y, Li Y
World journal of gastroenterology 2022 Jul 14;28(26):3164-3176
World journal of gastroenterology 2022 Jul 14;28(26):3164-3176
Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway.
Wang Y, Wang X, Li Y, Xue Z, Shao R, Li L, Zhu Y, Zhang H, Yang J
Pharmacological research 2022 Feb;176:106083
Pharmacological research 2022 Feb;176:106083
Extracellular vesicles produced by bone marrow mesenchymal stem cells overexpressing programmed death-ligand 1 ameliorate dextran sodium sulfate-induced ulcerative colitis in rats by regulating Th17/Treg cell balance through PTEN/PI3K/AKT/mTOR axis.
He H, Chen Q, Fan H, Leng XY, Zhu F, Gao F, Zhou Q, Dong Y, Yang J
Journal of gastroenterology and hepatology 2022 Dec;37(12):2243-2254
Journal of gastroenterology and hepatology 2022 Dec;37(12):2243-2254
Association of MARCH7 with tumor progression and T-cell infiltration in esophageal cancer.
Singh S, Bano A, Saraya A, Das P, Sharma R
Medical oncology (Northwood, London, England) 2022 Dec 30;40(1):67
Medical oncology (Northwood, London, England) 2022 Dec 30;40(1):67
Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy.
Zhou DX, Wang XH, Xu X, Chen WJ, Wei J, Chen TT, Wei H
Pharmaceutics 2022 Dec 13;14(12)
Pharmaceutics 2022 Dec 13;14(12)
Inhibition of PD-L1-mediated tumor-promoting signaling is involved in the anti-cancer activity of β-tocotrienol.
Sun Z, Yin S, Zhao C, Fan L, Hu H
Biochemical and biophysical research communications 2022 Aug 30;617(Pt 2):33-40
Biochemical and biophysical research communications 2022 Aug 30;617(Pt 2):33-40
Involvement of PD-L1-mediated tumor-intrinsic signaling and immune suppression in tumorigenic effect of α-tocopherol.
Sun Z, Yin S, Zhao C, Fan LH, Hu H
Carcinogenesis 2022 Apr 25;43(3):243-253
Carcinogenesis 2022 Apr 25;43(3):243-253
Methylation and Expression of the Exercise-Related TLR1 Gene Is Associated With Low Grade Glioma Prognosis and Outcome.
Lu L, Hu Y, Wang C, Jiang F, Wu C
Frontiers in molecular biosciences 2021;8:747933
Frontiers in molecular biosciences 2021;8:747933
Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice.
Sasaki K, Nishina S, Yamauchi A, Fukuda K, Hara Y, Yamamura M, Egashira K, Hino K
Cellular and molecular gastroenterology and hepatology 2021;11(3):739-762
Cellular and molecular gastroenterology and hepatology 2021;11(3):739-762
TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma.
Bao S, Jiang X, Jin S, Tu P, Lu J
Frontiers in oncology 2021;11:694145
Frontiers in oncology 2021;11:694145
Clinical significance of sarcoid-like reaction in lymph nodes of gastric cancer patients.
Itai Y, Ueda Y, Etoh T, Shirasaka Y, Shiroshita H, Shiraishi N, Daa T, Inomata M
Journal of surgical oncology 2021 Sep;124(3):293-300
Journal of surgical oncology 2021 Sep;124(3):293-300
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Xu HZ, Li TF, Wang C, Ma Y, Liu Y, Zheng MY, Liu ZJ, Chen JB, Li K, Sun SK, Komatsu N, Xu YH, Zhao L, Chen X
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
Deng Y, Su W, Zhu J, Ji H, Zhou X, Geng J, Zhu J, Zhang Q
Journal for immunotherapy of cancer 2021 Oct;9(10)
Journal for immunotherapy of cancer 2021 Oct;9(10)
The PD-1/PD-L1 pathway in murine hair cycle transition: a potential anagen phase regulator.
Zhou L, Wen L, Sheng Y, Lu J, Hu R, Wang X, Lu Z, Yang Q
Archives of dermatological research 2021 Nov;313(9):751-758
Archives of dermatological research 2021 Nov;313(9):751-758
Altered peripheral helper T cells in peripheral blood and muscle tissue of the patients with dermatomyositis.
Hou X, Yang C, Lin M, Tian B, Zhao S, Liu X, Yang P
Clinical and experimental medicine 2021 Nov;21(4):655-661
Clinical and experimental medicine 2021 Nov;21(4):655-661
PD-1/PD-L1 enhanced cisplatin resistance in gastric cancer through PI3K/AKT mediated P-gp expression.
Wu L, Cai S, Deng Y, Zhang Z, Zhou X, Su Y, Xu D
International immunopharmacology 2021 May;94:107443
International immunopharmacology 2021 May;94:107443
Relationship between PD-L1 expression, CD8+ T-cell infiltration and prognosis in intrahepatic cholangiocarcinoma patients.
Deng M, Li SH, Fu X, Yan XP, Chen J, Qiu YD, Guo RP
Cancer cell international 2021 Jul 12;21(1):371
Cancer cell international 2021 Jul 12;21(1):371
Nutritional supplements in combination with chemotherapy or targeted therapy reduces tumor progression in mice bearing triple-negative breast cancer.
Guo CH, Hsia S, Chung CH, Lin YC, Shih MY, Chen PC, Peng CL, Henning SM, Hsu GW, Li Z
The Journal of nutritional biochemistry 2021 Jan;87:108504
The Journal of nutritional biochemistry 2021 Jan;87:108504
Antifibrotic effect of Gancao Ganjiang decoction is mediated by PD-1 / TGF-β1 / IL-17A pathway in bleomycin-induced idiopathic pulmonary fibrosis.
Wang D, Gong L, Li Z, Chen H, Xu M, Rong R, Zhang Y, Zhu Q
Journal of ethnopharmacology 2021 Dec 5;281:114522
Journal of ethnopharmacology 2021 Dec 5;281:114522
Intratumoral administration of the Toll-like receptor 7/8 agonist 3M-052 enhances interferon-driven tumor immunogenicity and suppresses metastatic spread in preclinical triple-negative breast cancer.
Zanker DJ, Spurling AJ, Brockwell NK, Owen KL, Zakhour JM, Robinson T, Duivenvoorden HM, Hertzog PJ, Mullins SR, Wilkinson RW, Parker BS
Clinical & translational immunology 2020;9(9):e1177
Clinical & translational immunology 2020;9(9):e1177
BTLA Expression in Stage I-III Non-Small-Cell Lung Cancer and Its Correlation with PD-1/PD-L1 and Clinical Outcomes.
Li X, Xu Z, Cui G, Yu L, Zhang X
OncoTargets and therapy 2020;13:215-224
OncoTargets and therapy 2020;13:215-224
Isolation of DNA Aptamer Targeting PD-1 with an Antitumor Immunotherapy Effect.
Gao T, Pei R
ACS applied bio materials 2020 Oct 19;3(10):7080-7086
ACS applied bio materials 2020 Oct 19;3(10):7080-7086
Synergistic anti-liver cancer effects of curcumin and total ginsenosides.
Deng Z, Xu XY, Yunita F, Zhou Q, Wu YR, Hu YX, Wang ZQ, Tian XF
World journal of gastrointestinal oncology 2020 Oct 15;12(10):1091-1103
World journal of gastrointestinal oncology 2020 Oct 15;12(10):1091-1103
Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.
Yu L, Feng R, Zhu L, Hao Q, Chu J, Gu Y, Luo Y, Zhang Z, Chen G, Chen H
Science advances 2020 Nov;6(47)
Science advances 2020 Nov;6(47)
New insight on the correlation of metabolic status on (18)F-FDG PET/CT with immune marker expression in patients with non-small cell lung cancer.
Wang Y, Zhao N, Wu Z, Pan N, Shen X, Liu T, Wei F, You J, Xu W, Ren X
European journal of nuclear medicine and molecular imaging 2020 May;47(5):1127-1136
European journal of nuclear medicine and molecular imaging 2020 May;47(5):1127-1136
Programmed Cell Death-1: Programmed Cell Death-Ligand 1 Interaction Protects Human Cardiomyocytes Against T-Cell Mediated Inflammation and Apoptosis Response In Vitro.
Tay WT, Fang YH, Beh ST, Liu YW, Hsu LW, Yen CJ, Liu PY
International journal of molecular sciences 2020 Mar 31;21(7)
International journal of molecular sciences 2020 Mar 31;21(7)
Molecular subtyping reveals immune alterations in IDH wild-type lower-grade diffuse glioma.
Wu F, Li GZ, Liu HJ, Zhao Z, Chai RC, Liu YQ, Jiang HY, Zhai Y, Feng YM, Li RP, Zhang W
The Journal of pathology 2020 Jul;251(3):272-283
The Journal of pathology 2020 Jul;251(3):272-283
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
Yang J, Liu J, Sheng M, Zhang X, Liu M
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
Efficient Gene Silencing by Adenine Base Editor-Mediated Start Codon Mutation.
Wang X, Liu Z, Li G, Dang L, Huang S, He L, Ma Y, Li C, Liu M, Yang G, Huang X, Zhou F, Ma X
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):431-440
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):431-440
Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC.
Brockwell NK, Rautela J, Owen KL, Gearing LJ, Deb S, Harvey K, Spurling A, Zanker D, Chan CL, Cumming HE, Deng N, Zakhour JM, Duivenvoorden HM, Robinson T, Harris M, White M, Fox J, Ooi C, Kumar B, Thomson J, Potasz N, Swarbrick A, Hertzog PJ, Molloy TJ, Toole SO, Ganju V, Parker BS
NPJ precision oncology 2019;3:21
NPJ precision oncology 2019;3:21
Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease.
Zhou L, Liu D, Xie Y, Yao X, Li Y
Gut and liver 2019 Mar 15;13(4):430-439
Gut and liver 2019 Mar 15;13(4):430-439
Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer.
Gao M, Lin M, Moffitt RA, Salazar MA, Park J, Vacirca J, Huang C, Shroyer KR, Choi M, Georgakis GV, Sasson AR, Talamini MA, Kim J
British journal of cancer 2019 Jan;120(1):88-96
British journal of cancer 2019 Jan;120(1):88-96
Expression of PD-1/PD-L1 in head and neck squamous cell carcinoma and its clinical significance.
Chen SW, Li SH, Shi DB, Jiang WM, Song M, Yang AK, Li YD, Bei JX, Chen WK, Zhang Q
The International journal of biological markers 2019 Dec;34(4):398-405
The International journal of biological markers 2019 Dec;34(4):398-405
Estradiol Attenuates the Severity of Primary Toxoplasma gondii Infection-Induced Adverse Pregnancy Outcomes Through the Regulation of Tregs in a Dose-Dependent Manner.
Qiu J, Zhang R, Xie Y, Wang L, Ge K, Chen H, Liu X, Wu J, Wang Y
Frontiers in immunology 2018;9:1102
Frontiers in immunology 2018;9:1102
PD-1/PD-L1 Axis, Rather Than High-Mobility Group Alarmins or CD8+ Tumor-Infiltrating Lymphocytes, Is Associated With Survival in Head and Neck Squamous Cell Carcinoma Patients Who Received Surgical Resection.
Yang F, Zeng Z, Li J, Zheng Y, Wei F, Ren X
Frontiers in oncology 2018;8:604
Frontiers in oncology 2018;8:604
Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma.
Tang Y, He Y, Shi L, Yang L, Wang J, Lian Y, Fan C, Zhang P, Guo C, Zhang S, Gong Z, Li X, Xiong F, Li X, Li Y, Li G, Xiong W, Zeng Z
Oncotarget 2017 Jun 13;8(24):39001-39011
Oncotarget 2017 Jun 13;8(24):39001-39011
Immunological markers predict the prognosis of patients with squamous non-small cell lung cancer.
Jiang L, Zhao Z, Jiang S, Lin Y, Yang H, Xie Z, Lin Y, Long H
Immunologic research 2015 Jul;62(3):316-24
Immunologic research 2015 Jul;62(3):316-24
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 18106-1-AP(PD-1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 18106-1-AP(PD-1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 18106-1-AP(PD-1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PD-1/CD279 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PD-1/CD279. This antibody recognizes human antigen. The PD-1/CD279 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
