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Cell line expression
Protein structure
PDCD1
Programmed cell death 1CD279, hSLE1, PD-1, PD1, SLEB2
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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| Proteintech Group |  18106-1-AP |
77 references | Polyclonal |
WB
EL
ICC
IHC
FC
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| R&D Systems | AF1086 |
22 references | Polyclonal |
WB
EL
IHC
FC
BN
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| GeneTex | GTX20256 |
23 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| Novus Biologicals | AF1086 |
25 references | Polyclonal |
WB
IHC
FC
BN
|
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| LSBio | LS-C669062 |
Monoclonal |
WB
EL
ICC
IHC
|
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