Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM01176G - Provider product page
- Provider
- Leading Biology
- Product name
- PD1 / PDCD1 / CD279 (Programmed Cell Death 1) Antibody - With BSA and Azide
- Antibody type
- Monoclonal
- Description
- PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- PDCD1/922
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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