RA0554

antibody from Oursmab

Targeting: PDCD1 CD279, hSLE1, PD-1, PD1, SLEB2

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0554

Provider

Oursmab

Product name

Balstilimab (Biosimilar Reference Antibody) (PDCD1)

Antibody type

Monoclonal

Description

Balstilimab is a fully human monoclonal antibody designed as an immune checkpoint inhibitor. It specifically targets the programmed cell death protein 1 (PD-1) receptor, blocking its interaction with its ligands PD-L1 and PD-L2. By binding to PD-1 on T cells, it prevents the inhibitory ¡°off¡± signal, thereby reinvigorating the anti-tumor immune response. It was primarily investigated in clinical trials, both as a monotherapy and in combination with other agents, for the treatment of advanced cervical cancer and other solid tumors. Its development has progressed through Phase II trials.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Balstilimab (Biosimilar Reference Antibody) (PDCD1)-RA0554-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Balstilimab (Biosimilar Reference Antibody) (PDCD1)-RA0554 in a linear range of 0.18-125 ng/mL.