Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP2-48285 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal PD-1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 7 ml
- Storage
- Store at 4C.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PD-1 Antibody (PDCD1/922) - IHC-Prediluted [NBP2-48285] - Human Tonsil stained with PD1 (CD279) Monoclonal Antibody (PDCD1/922).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PD-1 Antibody (PDCD1/922) - IHC-Prediluted [NBP2-48285] - Human Tonsil stained with PD1 (CD279) Monoclonal Antibody (PDCD1/922).