Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN500459 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Programmed Cell Death 1 (PDCD1) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- PD-1 antibody was raised against a 16 amino acid peptide from near the center of human PD-1.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger.
Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
Zhong X, Bai C, Gao W, Strom TB, Rothstein TL
International immunology 2004 Aug;16(8):1181-8
International immunology 2004 Aug;16(8):1181-8
Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.
Holling TM, Schooten E, van Den Elsen PJ
Human immunology 2004 Apr;65(4):282-90
Human immunology 2004 Apr;65(4):282-90
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
Nishimura H, Nose M, Hiai H, Minato N, Honjo T
Immunity 1999 Aug;11(2):141-51
Immunity 1999 Aug;11(2):141-51
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
Ishida Y, Agata Y, Shibahara K, Honjo T
The EMBO journal 1992 Nov;11(11):3887-95
The EMBO journal 1992 Nov;11(11):3887-95
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of PD-1 in THP-1 cell lysate with AP30651PU-N at 1 ?g/ml in the (A) absence and (B) presence of blocking peptide.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of PD-1 in human brain tissue with AP30651PU-N at 5 ?g/ml.