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- Antibody Data
- Antigen structure
- References [4]
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- Product number
- HPA053249 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA053249, RRID:AB_2682089
- Product name
- Anti-RIT1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human RIT1, Gene description: Ras-like without CAAX 1, Alternative Gene Names: MGC125864, MGC125865, RIBB, RIT, ROC1, Validated applications: WB, Uniprot ID: Q92963, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Dysregulation of RAS proteostasis by autosomal-dominant LZTR1 mutation induces Noonan syndrome–like phenotypes in mice
LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion
New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
Guanine nucleotide exchange factor Epac2-dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells.
Abe T, Morisaki K, Niihori T, Terao M, Takada S, Aoki Y
JCI Insight 2024;9(22)
JCI Insight 2024;9(22)
LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion
Abe T, Kanno S, Niihori T, Terao M, Takada S, Aoki Y
Cell Death & Disease 2023;14(8)
Cell Death & Disease 2023;14(8)
New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
Takahara S, Inoue S, Miyagawa-Tomita S, Matsuura K, Nakashima Y, Niihori T, Matsubara Y, Saiki Y, Aoki Y
EBioMedicine 2019;42
EBioMedicine 2019;42
Guanine nucleotide exchange factor Epac2-dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells.
Emery AC, Xu W, Eiden MV, Eiden LE
The Journal of biological chemistry 2017 Jul 21;292(29):12220-12231
The Journal of biological chemistry 2017 Jul 21;292(29):12220-12231
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