RIT1

This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Description

Ras like without CAAX 1

Protein family

Cancer-related genes, Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

1:q22 (155897808 - 155911404)

Ensembl ID

ENSG00000143622  (ver. 99.38)

Orthologs

Mouse Rit1: ENSMUSG00000028057

UniProt

Q92963

neXtProt

NX_Q92963

Human splice variants
Mouse splice variants