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- Antibody Data
- Antigen structure
- References [20]
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- Product number
- 19666-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19666-1-AP, RRID:AB_10863656
- Product name
- GCK antibody
- Antibody type
- Polyclonal
- Description
- GCK antibody (Cat. #19666-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, rat, human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references β-Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control.
Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes.
Effects of propranolol on glucose metabolism in hemangioma-derived endothelial cells.
Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions.
Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
Functionalized gadofullerene ameliorates impaired glycolipid metabolism in type 2 diabetic mice.
Citrullination of glucokinase is linked to autoimmune diabetes.
FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway.
Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice.
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis.
NaoXinTong Capsules inhibit the development of diabetic nephropathy in db/db mice.
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease.
Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy.
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Liu J, Fu H, Kang F, Ning G, Ni Q, Wang W, Wang Q
Journal of diabetes 2023 May;15(5):409-418
Journal of diabetes 2023 May;15(5):409-418
Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes.
Watanabe H, Du W, Son J, Sui L, Asahara SI, Kurland IJ, Kuo T, Kitamoto T, Miyachi Y, de Cabo R, Accili D
Science translational medicine 2023 Feb;15(681):eabq4126
Science translational medicine 2023 Feb;15(681):eabq4126
Effects of propranolol on glucose metabolism in hemangioma-derived endothelial cells.
Yang K, Li X, Qiu T, Zhou J, Gong X, Lan Y, Ji Y
Biochemical pharmacology 2023 Dec;218:115922
Biochemical pharmacology 2023 Dec;218:115922
Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions.
Guo X, Liang K, Xia L, Zhang X, Liu J, Wang C, Li J, Li X, Hou X, Chen L
iScience 2023 Dec 15;26(12):108446
iScience 2023 Dec 15;26(12):108446
Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.
Long HP, Liu J, Xu PS, Xu KP, Li J, Tan GS
Phytochemistry 2022 Mar;195:113073
Phytochemistry 2022 Mar;195:113073
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
Ahat E, Bui S, Zhang J, da Veiga Leprevost F, Sharkey L, Reid W, Nesvizhskii AI, Paulson HL, Wang Y
The Journal of biological chemistry 2022 Aug;298(8):102219
The Journal of biological chemistry 2022 Aug;298(8):102219
Functionalized gadofullerene ameliorates impaired glycolipid metabolism in type 2 diabetic mice.
Wu J, Chen Y, Li X, Ran L, Liu X, Wang X, Zhen M, Shao S, Zeng L, Wang C, Liang B, Zhao J, Wu Y
Journal of genetics and genomics = Yi chuan xue bao 2022 Apr;49(4):364-376
Journal of genetics and genomics = Yi chuan xue bao 2022 Apr;49(4):364-376
Citrullination of glucokinase is linked to autoimmune diabetes.
Yang ML, Horstman S, Gee R, Guyer P, Lam TT, Kanyo J, Perdigoto AL, Speake C, Greenbaum CJ, Callebaut A, Overbergh L, Kibbey RG, Herold KC, James EA, Mamula MJ
Nature communications 2022 Apr 6;13(1):1870
Nature communications 2022 Apr 6;13(1):1870
FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway.
Zhuang L, Mao Y, Liu Z, Li C, Jin Q, Lu L, Tao R, Yan X, Chen K
Frontiers in cardiovascular medicine 2021;8:722908
Frontiers in cardiovascular medicine 2021;8:722908
Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation.
Bai X, Liao Y, Sun F, Xiao X, Fu S
Cell reports 2021 Sep 7;36(10):109659
Cell reports 2021 Sep 7;36(10):109659
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
He X, Li M, Yu H, Liu G, Wang N, Yin C, Tu Q, Narla G, Tao Y, Cheng S, Yin H
PLoS biology 2020 Dec;18(12):e3000803
PLoS biology 2020 Dec;18(12):e3000803
Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice.
Yang S, Chen Y, Duan Y, Ma C, Liu L, Li Q, Yang J, Li X, Zhao B, Wang Y, Qian K, Liu M, Zhu Y, Yang X, Han J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109389
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109389
Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.
Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, Li D, Chen L, Xiao Y, Chen W, Wang Q
Toxicology 2019 Aug 1;424:152236
Toxicology 2019 Aug 1;424:152236
Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis.
Song G, Lu Q, Fan H, Zhang X, Ge L, Tian R, Wang S, Feng T, Pan J, Feng J, Xiao Y, Yi X, Ren N, Wang L
Arthritis research & therapy 2019 Apr 3;21(1):87
Arthritis research & therapy 2019 Apr 3;21(1):87
NaoXinTong Capsules inhibit the development of diabetic nephropathy in db/db mice.
Yang S, Liu M, Chen Y, Ma C, Liu L, Zhao B, Wang Y, Li X, Zhu Y, Gao X, Kong D, Duan Y, Han J, Yang X
Scientific reports 2018 Jun 14;8(1):9158
Scientific reports 2018 Jun 14;8(1):9158
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Dong K, Wu M, Liu X, Huang Y, Zhang D, Wang Y, Yan LJ, Shi D
Free radical biology & medicine 2016 Dec;101:334-347
Free radical biology & medicine 2016 Dec;101:334-347
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Dong K, Ni H, Wu M, Tang Z, Halim M, Shi D
Biochemical and biophysical research communications 2016 Aug 5;476(4):204-211
Biochemical and biophysical research communications 2016 Aug 5;476(4):204-211
Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease.
Yan HM, Xia MF, Wang Y, Chang XX, Yao XZ, Rao SX, Zeng MS, Tu YF, Feng R, Jia WP, Liu J, Deng W, Jiang JD, Gao X
PloS one 2015;10(8):e0134172
PloS one 2015;10(8):e0134172
Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy.
Liu M, Pan Q, Chen Y, Yang X, Zhao B, Jia L, Zhu Y, Zhang B, Gao X, Li X, Han J, Duan Y
Scientific reports 2015 Jun 10;5:11219
Scientific reports 2015 Jun 10;5:11219
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Liu C, Lin JJ, Yang ZY, Tsai CC, Hsu JL, Wu YJ
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GCK antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GCK. This antibody recognizes human, mouse, rat antigen. The GCK antibody has been validated for the following applications: ELISA, WB analysis.
