GCK

gene product
HK4, MODY2
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009]
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350 antibodies from 31 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
GeneTex
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Biorbyt
14 antibodies
antibodies-online
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Novus Biologicals
13 antibodies
OriGene
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Abnova Corporation
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4 antibodies
Abgent
5 antibodies
NSJ Bioreagents
2 antibodies
Invitrogen Antibodies
6 antibodies
LifeSpan BioSciences, Inc.
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7 antibodies
St John's Laboratory
6 antibodies
Bioworld Technology, Inc
2 antibodies
Bioss
1 antibody
Atlas Antibodies
2 antibodies
Proteintech Group
2 antibodies
Affinity Biosciences
1 antibody
ProSci
1 antibody
RabMAbs
4 antibodies
MyBioSource
8 antibodies
Arigo
2 antibodies
RayBiotech, Inc.
2 antibodies
Aviva Systems Biology
3 antibodies
Creative Biolabs
4 antibodies
Creative Diagnostics
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Abbkine Scientific Co.Ltd.
1 antibody
R&D Systems
1 antibody
Boster Biological Technology
1 antibody
United States Biological
52 antibodies
Sigma-Aldrich
4 antibodies