Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB13232 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13232, RRID:AB_10554925
- Product name
- NCSTN polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of NCSTN.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Loss of nicastrin elicits an apoptotic phenotype in mouse embryos.
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.
Nguyen V, Hawkins C, Bergeron C, Supala A, Huang J, Westaway D, St George-Hyslop P, Rozmahel R
Brain research 2006 May 1;1086(1):76-84
Brain research 2006 May 1;1086(1):76-84
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
Periz G, Fortini ME
Journal of neuroscience research 2004 Aug 1;77(3):309-22
Journal of neuroscience research 2004 Aug 1;77(3):309-22
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.
Selkoe DJ
Trends in cell biology 1998 Nov;8(11):447-53
Trends in cell biology 1998 Nov;8(11):447-53
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of NCSTN in mouse brain tissue lysate with NCSTN polyclonal antibody (Cat # PAB13232) at (A) 0.5 and (B) 1 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of NCSTN in human brain tissue with NCSTN polyclonal antibody (Cat # PAB13232) at 2.5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)