MAB313

antibody from Novus Biologicals

Targeting: TEK CD202b, TIE-2, TIE2, VMCM, VMCM1

Western blot (Data presented on provider website)

Antibody Data

Product number

MAB313

Provider

Novus Biologicals

Product name

Mouse Monoclonal Tie-2 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from ascites. Detects human Tie-2 in direct ELISAs and Western blots. Shows approximately 15% cross-reactivity with recombinant mouse Tie-2 and less than 1% cross-reactivity with recombinant human Tie-1.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

500 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Down-regulation of vascular endothelial growth factor receptor 2 is a major molecular determinant of proteasome inhibitor-mediated antiangiogenic action in endothelial cells.

Meissner M, Reichenbach G, Stein M, Hrgovic I, Kaufmann R, Gille J
Cancer research 2009 Mar 1;69(5):1976-84

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Monoclonal antibody classification based on epitope-binding using differential antigen disruption.

Shi E, Fury W, Li W, Mikulka W, Aldrich T, Rafique A, Chen G, Hoffenberg S, Daly TJ, Radziejewski C
Journal of immunological methods 2006 Jul 31;314(1-2):9-20

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Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis.

Giuliani N, Colla S, Lazzaretti M, Sala R, Roti G, Mancini C, Bonomini S, Lunghi P, Hojden M, Genestreti G, Svaldi M, Coser P, Fattori PP, Sammarelli G, Gazzola GC, Bataille R, Almici C, Caramatti C, Mangoni L, Rizzoli V
Blood 2003 Jul 15;102(2):638-45