Explore
Validate
Learn
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- FAB3131P - Provider product page
- Provider
- R&D Systems
- Product name
- Human Tie-2 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Tie-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tie-1, recombinant mouse Tie-2, or recombinant zebrafish Tie-2 is observed.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAA61139- Isotype
- IgG
- Antibody clone number
- 83715
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure.
Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer.
slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells.
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.
Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer.
Human haemato-endothelial precursors: cord blood CD34+ cells produce haemogenic endothelium.
IFATS collection: Fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism.
Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy.
Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
Triantafyllou E, Pop OT, Possamai LA, Wilhelm A, Liaskou E, Singanayagam A, Bernsmeier C, Khamri W, Petts G, Dargue R, Davies SP, Tickle J, Yuksel M, Patel VC, Abeles RD, Stamataki Z, Curbishley SM, Ma Y, Wilson ID, Coen M, Woollard KJ, Quaglia A, Wendon J, Thursz MR, Adams DH, Weston CJ, Antoniades CG
Gut 2018 Feb;67(2):333-347
Gut 2018 Feb;67(2):333-347
Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer.
Forget MA, Voorhees JL, Cole SL, Dakhlallah D, Patterson IL, Gross AC, Moldovan L, Mo X, Evans R, Marsh CB, Eubank TD
PloS one 2014;9(6):e98623
PloS one 2014;9(6):e98623
slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells.
Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, Bugatti M, Codazzi M, Pinter PC, Schäkel K, Tamassia N, Cassatella MA
Nature communications 2014;5:3029
Nature communications 2014;5:3029
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.
Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, Leroy X, Prevarskaya N, Gkika D, Bussolati B
BMC cancer 2014 Dec 12;14:939
BMC cancer 2014 Dec 12;14:939
Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer.
Schauer D, Starlinger P, Reiter C, Jahn N, Zajc P, Buchberger E, Bachleitner-Hofmann T, Bergmann M, Stift A, Gruenberger T, Brostjan C
PloS one 2012;7(9):e44450
PloS one 2012;7(9):e44450
Human haemato-endothelial precursors: cord blood CD34+ cells produce haemogenic endothelium.
Pelosi E, Castelli G, Martin-Padura I, Bordoni V, Santoro S, Conigliaro A, Cerio AM, De Santis Puzzonia M, Marighetti P, Biffoni M, Alonzi T, Amicone L, Alcalay M, Bertolini F, Testa U, Tripodi M
PloS one 2012;7(12):e51109
PloS one 2012;7(12):e51109
IFATS collection: Fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism.
Suga H, Eto H, Shigeura T, Inoue K, Aoi N, Kato H, Nishimura S, Manabe I, Gonda K, Yoshimura K
Stem cells (Dayton, Ohio) 2009 Jan;27(1):238-49
Stem cells (Dayton, Ohio) 2009 Jan;27(1):238-49
Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, Yagita H, Koyanagi M, Kondo Y, Yuo A
Journal of cellular physiology 2008 Oct;217(1):261-80
Journal of cellular physiology 2008 Oct;217(1):261-80
The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy.
Cai J, Kehoe O, Smith GM, Hykin P, Boulton ME
Investigative ophthalmology & visual science 2008 May;49(5):2163-71
Investigative ophthalmology & visual science 2008 May;49(5):2163-71
Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
British journal of haematology 2006 Dec;135(5):703-14
British journal of haematology 2006 Dec;135(5):703-14
No comments: Submit comment
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Tie-2 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human Tie-2 PE-conjugated Monoclonal Antibody (Catalog # FAB3131P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
