Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 21042-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21042-1-AP, RRID:AB_10732602
- Product name
- NR1I3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NR1I3 antibody (Cat. #21042-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integrated approach for exploring the mechanism of cholestatic liver injury induced by Psoraleae Fructus.
Constitutive Androstane Receptor in Macrophages Regulates Toll-Like Receptor 4-Mediated Innate Immune Responses Against Endotoxemic Liver Injury.
NR1I3 inhibits colorectal cancer growth by enhancing PCK1-mediated gluconeogenesis.
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Panaxytriol upregulates CYP3A4 expression through the interaction between nuclear regulators and DNA response elements.
A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction.
Oleanolic Acid and Ursolic Acid Induce UGT1A1 Expression in HepG2 Cells by Activating PXR Rather Than CAR.
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
Liang H, Zhang Y, Zhu R, Zhang B, Zhang J, Hao X, Zhao G, Shen X, Wei K, Zhang Q, Li W, Liu T, Yu L
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120237
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120237
Constitutive Androstane Receptor in Macrophages Regulates Toll-Like Receptor 4-Mediated Innate Immune Responses Against Endotoxemic Liver Injury.
Cao R, Zhao T, Wang Y, Song S, Li Y, Hou M, Zhang Y, Wong S, Wang S, Wang Y, Peng H, Huang M, Jiang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e06725
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e06725
NR1I3 inhibits colorectal cancer growth by enhancing PCK1-mediated gluconeogenesis.
Shi H, Wu Z, Liu J, Wang T, Niu Z, Zhang W, Chen B, Mao X, Huang Y, Li J, Qi H, Wang X, Chen L, Li Q
Chemico-biological interactions 2025 Nov 1;421:111734
Chemico-biological interactions 2025 Nov 1;421:111734
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Qian G, Zang H, Tang J, Zhang H, Yu J, Jia H, Zhang X, Zhou J
PLoS pathogens 2024 Sep;20(9):e1012541
PLoS pathogens 2024 Sep;20(9):e1012541
Panaxytriol upregulates CYP3A4 expression through the interaction between nuclear regulators and DNA response elements.
Yan J, Gu Q, Meng C, Liu J, Liu F, Xia C
Journal of ethnopharmacology 2023 Jun 28;310:116398
Journal of ethnopharmacology 2023 Jun 28;310:116398
A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction.
Li H, Wang YG, Ma ZC, Yun-Hang G, Ling S, Teng-Fei C, Guang-Ping Z, Gao Y
Xenobiotica; the fate of foreign compounds in biological systems 2021 Jul;51(7):752-763
Xenobiotica; the fate of foreign compounds in biological systems 2021 Jul;51(7):752-763
Oleanolic Acid and Ursolic Acid Induce UGT1A1 Expression in HepG2 Cells by Activating PXR Rather Than CAR.
Yao N, Zeng C, Zhan T, He F, Liu M, Liu F, Zhang H, Xiong Y, Xia C
Frontiers in pharmacology 2019;10:1111
Frontiers in pharmacology 2019;10:1111
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
Hu Q, Yao N, Wu J, Liu M, Liu F, Zhang H, Xiong Y, Xia C
Biochemical pharmacology 2019 Jan;159:32-39
Biochemical pharmacology 2019 Jan;159:32-39
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The NR1I3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human NR1I3. This antibody recognizes human, mouse, rat antigen. The NR1I3 antibody has been validated for the following applications: ELISA, WB analysis.