NR1I3

gene product
CAR, CAR1, MB67
This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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413 antibodies from 29 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
24 antibodies
R&D Systems
2 antibodies
antibodies-online
133 antibodies
GeneTex
6 antibodies
OriGene
24 antibodies
Biorbyt
21 antibodies
Affinity Biosciences
1 antibody
LifeSpan BioSciences, Inc.
81 antibodies
Bioworld Technology, Inc
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Aviva Systems Biology
8 antibodies
Abnova Corporation
7 antibodies
Invitrogen Antibodies
6 antibodies
Acris Antibodies GmbH
2 antibodies
ProSci
4 antibodies
Boster Biological Technology
2 antibodies
St John's Laboratory
2 antibodies
Proteintech Group
1 antibody
Abgent
4 antibodies
United States Biological
50 antibodies
Creative Biolabs
10 antibodies
MyBioSource
5 antibodies
Creative Diagnostics
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
RayBiotech, Inc.
1 antibody
Abbexa
3 antibodies
GenWay
2 antibodies
Sigma-Aldrich
3 antibodies
EMD Millipore
1 antibody