Tissue expression
Cell line expression

FCGR3A

gene product
CD16, CD16a, FCG3, FCGR3 
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
More gene data

Antibodies

 

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2687 antibodies from 48 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
469 antibodies
antibodies-online
800 antibodies
R&D Systems
56 antibodies
GeneTex
22 antibodies
BioLegend
97 antibodies
OriGene
44 antibodies
NSJ Bioreagents
7 antibodies
Acris Antibodies GmbH
57 antibodies
Biorbyt
63 antibodies
Proteintech Group
6 antibodies
Antibodies.com
17 antibodies
Abnova Corporation
28 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
LifeSpan BioSciences, Inc.
142 antibodies
Invitrogen Antibodies
4 antibodies
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Atlas Antibodies
1 antibody
Boster Biological Technology
7 antibodies
Abbiotec
4 antibodies
Bioworld Technology, Inc
1 antibody
NovoPro Bioscience Inc.
4 antibodies
Abbkine Scientific Co.Ltd.
3 antibodies
Abgent
3 antibodies
St John's Laboratory
5 antibodies
HUABIO Research
1 antibody
Aviva Systems Biology
18 antibodies
Creative Biolabs
503 antibodies
MyBioSource
13 antibodies
ABEOMICS Inc.
2 antibodies
Creative Diagnostics
27 antibodies
RabMAbs
2 antibodies
EMD Millipore
2 antibodies
Miltenyi Biotec
33 antibodies
Cell Signaling Technology, Inc
5 antibodies
STEMCELL Technologies Inc
14 antibodies
Abbexa
41 antibodies
GenWay
25 antibodies
MilliporeSigma / Merck KGaA
6 antibodies
United States Biological
40 antibodies
Leading Biology
13 antibodies
eBioscience, An Affymetrix Company
43 antibodies
ProSci
6 antibodies
Sino Biological Inc.
6 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody