302015

FCGR3A antibody from BioLegend
CD16, CD16a, FCG3, FCGR3

Antibody data

Product number
302015
Provider
BioLegend
Proper citation
BioLegend Cat#302015, RRID:AB_314215
Product name
PE/Cy7 anti-human CD16
Provider product page
BioLegend - 302015
Antibody type
Monoclonal
Antigen
CD16
Description
CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. It is over 95% homologous to CD16a in extracellular domain and is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
Reactivity
Human, Simian
Host
Mouse
Conjugate
Infrared dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -