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- References [4]
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- Western blot [1]
- Immunocytochemistry [2]
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- Product number
- ABIN499351 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Activating Transcription Factor 6 (ATF6) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Human ATF6 (C-Terminus) Peptide (AP30088CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The unfolded protein response.
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.
The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications.
Liu CY, Kaufman RJ
Journal of cell science 2003 May 15;116(Pt 10):1861-2
Journal of cell science 2003 May 15;116(Pt 10):1861-2
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K
Cell 2001 Dec 28;107(7):881-91
Cell 2001 Dec 28;107(7):881-91
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.
Haze K, Yoshida H, Yanagi H, Yura T, Mori K
Molecular biology of the cell 1999 Nov;10(11):3787-99
Molecular biology of the cell 1999 Nov;10(11):3787-99
The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications.
Little E, Ramakrishnan M, Roy B, Gazit G, Lee AS
Critical reviews in eukaryotic gene expression 1994;4(1):1-18
Critical reviews in eukaryotic gene expression 1994;4(1):1-18
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of ATF6 in MCF7 cell lysate with AP30088PU-N ATF6 antibody at (A) 0.5 and (B) 1 μg/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of ATF6 in MCF7 cells with AP30088PU-N ATF6 antibody at 10 μg/ml.
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemical staining of MCF7 cells using AP30088PU-N ATF6 antibody at 10 ?g/ml.
