Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1001735 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- ATF6 antibody was raised against a 17 amino acid peptide from near the amino terminus of human ATF6.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references The unfolded protein response.
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.
The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications.
Liu CY, Kaufman RJ
Journal of cell science 2003 May 15;116(Pt 10):1861-2
Journal of cell science 2003 May 15;116(Pt 10):1861-2
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K
Cell 2001 Dec 28;107(7):881-91
Cell 2001 Dec 28;107(7):881-91
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.
Haze K, Yoshida H, Yanagi H, Yura T, Mori K
Molecular biology of the cell 1999 Nov;10(11):3787-99
Molecular biology of the cell 1999 Nov;10(11):3787-99
The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications.
Little E, Ramakrishnan M, Roy B, Gazit G, Lee AS
Critical reviews in eukaryotic gene expression 1994;4(1):1-18
Critical reviews in eukaryotic gene expression 1994;4(1):1-18
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