MAB6951

antibody from R&D Systems

Targeting: XCL1 ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

MAB6951

Provider

R&D Systems

Product name

Human XCL1/Lymphotactin Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from ascites. Detects human XCL1/Lymphotactin in ELISAs and Western blots. In sandwich ELISAs, less than 0.15% cross-reactivity was observed with recombinant mouse MCP-5, recombinant human (rh) MIP-3 beta , rhGRO alpha , rhTGF-alpha , rhGRO gamma , rhActivin RII Fc Chimera, rhIGF-II, or rhIL-15.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

P47992


Isotype

IgG

Antibody clone number

109001

Vial size

500 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Targeting Influenza Virus Hemagglutinin to Xcr1⁺ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses.

Gudjonsson A, Lysén A, Balan S, Sundvold-Gjerstad V, Arnold-Schrauf C, Richter L, Bækkevold ES, Dalod M, Bogen B, Fossum E
Journal of immunology (Baltimore, Md. : 1950) 2017 Apr 1;198(7):2785-2795

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The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1.

Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman BF, Fauci AS, Lusso P
PLoS pathogens 2013;9(12):e1003852

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Mycobacterium tuberculosis antigen Wag31 induces expression of C-chemokine XCL2 in macrophages.

Cao W, Tang S, Yuan H, Wang H, Zhao X, Lu H
Current microbiology 2008 Sep;57(3):189-94