XCL1

This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014]

Description

X-C motif chemokine ligand 1

Tissue specificity

Tissue enhanced (lymphoid tissue)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

1 (168576605 - 168582069)

Ensembl ID

ENSG00000143184  (ver. 103.38)

Orthologs

-

UniProt

P47992

neXtProt

NX_P47992

Human splice variants

Protein structure