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- References [17]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 55247-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55247-1-AP, RRID:AB_10836939
- Product name
- MAP4K4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MAP4K4 antibody (Cat. #55247-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphatidylserine-Based Liposomes Encapsulating DMX-5804 Protect Against Doxorubicin-Induced Cardiotoxicity.
N(6)-methyladenosine Reader IGF2BP2-modified HMMR Promotes Non-small Cell Lung Cancer Metastasis via Interaction with MAP4K4.
The long noncoding RNA lnc-FANCI-2 intrinsically restricts RAS signaling in human papillomavirus type 16-infected cervical cancer cells.
Overcoming radioresistance of breast cancer cells with MAP4K4 inhibitors.
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
Nanoparticle-Patch System for Localized, Effective, and Sustained miRNA Administration into Infarcted Myocardium to Alleviate Myocardial Ischemia-Reperfusion Injury.
RANKL/RANK contributes to the pathological process of type 2 diabetes mellitus through TRAF3 activation of NIK.
Artesunate improves glucose and lipid metabolism in db/db mice by regulating the metabolic profile and the MAPK/PI3K/Akt signalling pathway.
Comprehensive analysis of senescence-related genes and immune infiltration in intervertebral disc degeneration: a meta-data approach utilizing bulk and single-cell RNA sequencing data.
Transcriptome profiling of microRNAs reveals potential mechanisms of manual therapy alleviating neuropathic pain through microRNA-547-3p-mediated Map4k4/NF-κb signaling pathway.
Targeting miR-30d reverses pathological cardiac hypertrophy.
MiR-181c suppresses triple-negative breast cancer tumorigenesis by targeting MAP4K4.
Construction and validation of a novel prognostic signature of microRNAs in lung adenocarcinoma.
MAP4K4 induces early blood-brain barrier damage in a murine subarachnoid hemorrhage model.
Global Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice.
Parallel-Reaction-Monitoring-Based Proteome-Wide Profiling of Differential Kinase Protein Expression during Prostate Cancer Metastasis in Vitro.
Regulation of MAP4K4 gene expression by RNA interference through an engineered theophylline-dependent hepatitis delta virus ribozyme switch.
Tetterton-Kellner J, Jensen BC, Nguyen J
bioRxiv : the preprint server for biology 2026 Feb 13;
bioRxiv : the preprint server for biology 2026 Feb 13;
N(6)-methyladenosine Reader IGF2BP2-modified HMMR Promotes Non-small Cell Lung Cancer Metastasis via Interaction with MAP4K4.
Zhang J, Zhang M, Qiu A, Li C, Chen Q, Li J, Zeng Y, Zhu J, Huang JA, Zhang X, Liu Z
International journal of biological sciences 2025;21(4):1391-1409
International journal of biological sciences 2025;21(4):1391-1409
The long noncoding RNA lnc-FANCI-2 intrinsically restricts RAS signaling in human papillomavirus type 16-infected cervical cancer cells.
Liu H, Yu L, Majerciak V, Meyer TJ, Yi M, Johnson PF, Cam M, Lowy DR, Zheng ZM
eLife 2025 Aug 29;13
eLife 2025 Aug 29;13
Overcoming radioresistance of breast cancer cells with MAP4K4 inhibitors.
Kwon YS, Lee MG, Kim NY, Nam GS, Nam KS, Jang H, Kim S
Scientific reports 2024 Mar 28;14(1):7410
Scientific reports 2024 Mar 28;14(1):7410
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
Song F, Zhang Z, Liu W, Xu T, Hu X, Wang Q, Zhang W, Ge L, Zhang C, Hu Q, Qin H, Zhang S, Ren X, Fan W, Zhang Y, Huang P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
Nanoparticle-Patch System for Localized, Effective, and Sustained miRNA Administration into Infarcted Myocardium to Alleviate Myocardial Ischemia-Reperfusion Injury.
Chen X, Chen H, Zhu L, Zeng M, Wang T, Su C, Vulugundam G, Gokulnath P, Li G, Wang X, Yao J, Li J, Cretoiu D, Chen Z, Bei Y
ACS nano 2024 Jul 17;
ACS nano 2024 Jul 17;
RANKL/RANK contributes to the pathological process of type 2 diabetes mellitus through TRAF3 activation of NIK.
Yu J, Tian N, Hu Y, Jin T
International immunopharmacology 2024 Dec 5;142(Pt A):113008
International immunopharmacology 2024 Dec 5;142(Pt A):113008
Artesunate improves glucose and lipid metabolism in db/db mice by regulating the metabolic profile and the MAPK/PI3K/Akt signalling pathway.
Chen L, Wang J, Ren Y, Ma Y, Liu J, Jiang H, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155382
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155382
Comprehensive analysis of senescence-related genes and immune infiltration in intervertebral disc degeneration: a meta-data approach utilizing bulk and single-cell RNA sequencing data.
Deng YJ, Wang XG, Li Z, Wang B, Li J, Ma J, Xue X, Tian X, Liu QC, Liu JY, Zhang Y, Yuan B
Frontiers in molecular biosciences 2023;10:1296782
Frontiers in molecular biosciences 2023;10:1296782
Transcriptome profiling of microRNAs reveals potential mechanisms of manual therapy alleviating neuropathic pain through microRNA-547-3p-mediated Map4k4/NF-κb signaling pathway.
Yao C, Ren J, Huang R, Tang C, Cheng Y, Lv Z, Kong L, Fang S, Tao J, Fu Y, Zhu Q, Fang M
Journal of neuroinflammation 2022 Sep 1;19(1):211
Journal of neuroinflammation 2022 Sep 1;19(1):211
Targeting miR-30d reverses pathological cardiac hypertrophy.
Li J, Sha Z, Zhu X, Xu W, Yuan W, Yang T, Jin B, Yan Y, Chen R, Wang S, Yao J, Xu J, Wang Z, Li G, Das S, Yang L, Xiao J
EBioMedicine 2022 Jul;81:104108
EBioMedicine 2022 Jul;81:104108
MiR-181c suppresses triple-negative breast cancer tumorigenesis by targeting MAP4K4.
Xie D, Li S, Wu T, Wang X, Fang L
Pathology, research and practice 2022 Feb;230:153763
Pathology, research and practice 2022 Feb;230:153763
Construction and validation of a novel prognostic signature of microRNAs in lung adenocarcinoma.
Li W, Liu S, Su S, Chen Y, Sun G
PeerJ 2021;9:e10470
PeerJ 2021;9:e10470
MAP4K4 induces early blood-brain barrier damage in a murine subarachnoid hemorrhage model.
Zou Z, Dong YS, Liu DD, Li G, Hao GZ, Gao X, Pan PY, Liang GB
Neural regeneration research 2021 Feb;16(2):325-332
Neural regeneration research 2021 Feb;16(2):325-332
Global Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice.
Zhang J, Tang N, Zhao Y, Zhao R, Fu X, Zhao D, Zhao Y, Huang L, Li C, Qiu Y, Xue B, Fang L
Journal of proteome research 2020 Apr 3;19(4):1788-1799
Journal of proteome research 2020 Apr 3;19(4):1788-1799
Parallel-Reaction-Monitoring-Based Proteome-Wide Profiling of Differential Kinase Protein Expression during Prostate Cancer Metastasis in Vitro.
Miao W, Yuan J, Li L, Wang Y
Analytical chemistry 2019 Aug 6;91(15):9893-9900
Analytical chemistry 2019 Aug 6;91(15):9893-9900
Regulation of MAP4K4 gene expression by RNA interference through an engineered theophylline-dependent hepatitis delta virus ribozyme switch.
Cheng H, Zhang Y, Wang H, Sun N, Liu M, Chen H, Pei R
Molecular bioSystems 2016 Oct 18;12(11):3370-3376
Molecular bioSystems 2016 Oct 18;12(11):3370-3376
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 55247-1-AP(MAP4K4 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 55247-1-AP(MAP4K4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MAP4K4 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human MAP4K4. This antibody recognizes human,mouse,rat antigen. The MAP4K4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
