GLRX2

gene product
bA101E13.1, GRX2
The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
164 antibodies from 25 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
66 antibodies
GeneTex
2 antibodies
Biorbyt
9 antibodies
Aviva Systems Biology
2 antibodies
Acris Antibodies GmbH
4 antibodies
OriGene
2 antibodies
Novus Biologicals
6 antibodies
Invitrogen Antibodies
4 antibodies
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
25 antibodies
Abnova Corporation
5 antibodies
Atlas Antibodies
2 antibodies
NSJ Bioreagents
1 antibody
Boster Biological Technology
1 antibody
ProSci
1 antibody
Bioworld Technology, Inc
1 antibody
MyBioSource
4 antibodies
Affinity Biosciences
1 antibody
St John's Laboratory
1 antibody
Creative Biolabs
8 antibodies
Sigma-Aldrich
2 antibodies
United States Biological
2 antibodies
Creative Diagnostics
1 antibody