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- Product number
- 13381-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13381-1-AP, RRID:AB_10643373
- Product name
- GLRX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GLRX2 antibody (Cat. #13381-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Glutaredoxin 2 Protects Lens Epithelial Cells From Ferroptosis by Preventing HNRNPA2B1 S-Glutathionylation in Diabetes-Mediated Cataractogenesis.
Grx2 maintains GSH/GSSG homeostasis to enhance GPX4-mediated ferroptosis defense in UVB irradiation induced cataract.
RSL3 sensitizes glioma cells to ionizing radiation by suppressing TGM2-dependent DNA damage repair and epithelial-mesenchymal transition.
Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells.
Hepatic AMPK signaling dynamic activation in response to REDOX balance are sentinel biomarkers of exercise and antioxidant intervention to improve blood glucose control.
Glutaredoxin 2 protects cardiomyocytes from hypoxia/reoxygenation-induced injury by suppressing apoptosis, oxidative stress, and inflammation via enhancing Nrf2 signaling.
Compartmentally scavenging hepatic oxidants through AMPK/SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism.
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Redox proteins are constitutively secreted by skeletal muscle.
Li X, Guo Z, Li C, Zhang S, Liang C, Chen X, Guo C, Yan H
Investigative ophthalmology & visual science 2025 Dec 1;66(15):58
Investigative ophthalmology & visual science 2025 Dec 1;66(15):58
Grx2 maintains GSH/GSSG homeostasis to enhance GPX4-mediated ferroptosis defense in UVB irradiation induced cataract.
Guo C, Guo Y, Zhang J, Wang J, Su L, Ning X, Chen X, Yan H
Experimental eye research 2025 Aug;257:110421
Experimental eye research 2025 Aug;257:110421
RSL3 sensitizes glioma cells to ionizing radiation by suppressing TGM2-dependent DNA damage repair and epithelial-mesenchymal transition.
Wang X, Shi W, Li M, Xin Y, Jiang X
Redox biology 2024 Dec;78:103438
Redox biology 2024 Dec;78:103438
Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells.
Joshi PR, Sadre S, Guo XA, McCoy JG, Mootha VK
The Journal of biological chemistry 2023 Sep;299(9):105075
The Journal of biological chemistry 2023 Sep;299(9):105075
Hepatic AMPK signaling dynamic activation in response to REDOX balance are sentinel biomarkers of exercise and antioxidant intervention to improve blood glucose control.
Wu M, Zhao A, Yan X, Gao H, Zhang C, Liu X, Luo Q, Xie F, Liu S, Shi D
eLife 2022 Sep 26;11
eLife 2022 Sep 26;11
Glutaredoxin 2 protects cardiomyocytes from hypoxia/reoxygenation-induced injury by suppressing apoptosis, oxidative stress, and inflammation via enhancing Nrf2 signaling.
Li C, Xin H, Shi Y, Mu J
International immunopharmacology 2021 May;94:107428
International immunopharmacology 2021 May;94:107428
Compartmentally scavenging hepatic oxidants through AMPK/SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism.
Wu M, Zhang C, Xie M, Zhen Y, Lai B, Liu J, Qiao L, Liu S, Shi D
Free radical biology & medicine 2021 May 20;168:117-128
Free radical biology & medicine 2021 May 20;168:117-128
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
Wen J, Li X, Zheng S, Xiao Y
Brain research 2020 Oct 15;1745:146946
Brain research 2020 Oct 15;1745:146946
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Dong K, Wu M, Liu X, Huang Y, Zhang D, Wang Y, Yan LJ, Shi D
Free radical biology & medicine 2016 Dec;101:334-347
Free radical biology & medicine 2016 Dec;101:334-347
Redox proteins are constitutively secreted by skeletal muscle.
Manabe Y, Takagi M, Nakamura-Yamada M, Goto-Inoue N, Taoka M, Isobe T, Fujii NL
The journal of physiological sciences : JPS 2014 Nov;64(6):401-9
The journal of physiological sciences : JPS 2014 Nov;64(6):401-9
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The GLRX2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GLRX2. This antibody recognizes human,mouse,rat antigen. The GLRX2 antibody has been validated for the following applications: ELISA, WB analysis.
