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- References [5]
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- Immunohistochemistry [1]
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- Product number
- ABIN953298 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (AA 1065-1097), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 1065-1097, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes.
Role of mitogen-activated protein kinase kinase 4 in cancer.
MEKK4 is an effector of the embryonic TRAF4 for JNK activation.
Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II.
CIN85 regulates the ability of MEKK4 to activate the p38 MAP kinase pathway.
Grucza RA, Johnson EO, Krueger RF, Breslau N, Saccone NL, Chen LS, Derringer J, Agrawal A, Lynskey M, Bierut LJ
Addiction biology 2010 Jul;15(3):346-57
Addiction biology 2010 Jul;15(3):346-57
Role of mitogen-activated protein kinase kinase 4 in cancer.
Whitmarsh AJ, Davis RJ
Oncogene 2007 May 14;26(22):3172-84
Oncogene 2007 May 14;26(22):3172-84
MEKK4 is an effector of the embryonic TRAF4 for JNK activation.
Abell AN, Johnson GL
The Journal of biological chemistry 2005 Oct 28;280(43):35793-6
The Journal of biological chemistry 2005 Oct 28;280(43):35793-6
Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II.
Derbyshire ZE, Halfter UM, Heimark RL, Sy TH, Vaillancourt RR
Molecular and cellular biochemistry 2005 Mar;271(1-2):77-90
Molecular and cellular biochemistry 2005 Mar;271(1-2):77-90
CIN85 regulates the ability of MEKK4 to activate the p38 MAP kinase pathway.
Aissouni Y, Zapart G, Iovanna JL, Dikic I, Soubeyran P
Biochemical and biophysical research communications 2005 Dec 16;338(2):808-14
Biochemical and biophysical research communications 2005 Dec 16;338(2):808-14
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
