28761-1-AP

antibody from Proteintech Group

Targeting: MAP3K20 MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

28761-1-AP

Provider

Proteintech Group

Product name

ZAK antibody

Antibody type

Polyclonal

Description

KD/KO validated ZAK antibody (Cat. #28761-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia.

Park J, Kim SH, Park J, Park H, Kim H, Kim DW, Lim C
Leukemia 2026 May;40(5):955-969

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Inhibition the MAP3K20-mediated ribotoxic stress response pathway downregulates M1 macrophage polarization in ulcerative colitis.

Xia WY, Ma XY, Zhu ZM, Peng Y, Sun N, Guo JA, Xie CY, Xie LS, Zhang TE, Wu QF, Wang JM
International immunopharmacology 2026 Jan 1;168(Pt 1):115759

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ZAKα Induces Pyroptosis of Colonic Epithelium Via the Caspase-11/GSDMD Pathway to Aggravate Colitis.

Li S, Chen M, Zheng S, Abudourexiti W, Zhu F, Wang Z, Guo Y, Yu Z, Yang Z, Zhang L, Ding C, Gong J
Inflammation 2025 Oct;48(5):3235-3251

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Linoleic Acid Enhances Renal Tubular Epithelial Cells Autophagy Caused by Calcium Oxalate Monohydrate Crystals.

Ma W, Wei W, Dong Y, Zhao Y, Xia T, Wang X, Han C
Journal of cellular and molecular medicine 2024 Dec;28(24):e70250

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The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model.

Li Y, Xu J, Guo X, Li Z, Cao L, Liu S, Guo Y, Wang G, Luo Y, Zhang Z, Wei X, Zhao Y, Liu T, Wang X, Xia H, Kuang M, Guo Q, Li J, Chen L, Wang Y, Li Q, Wang F, Liu Q, You F
Genome biology 2023 Feb 1;24(1):20