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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB859P - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Dtk/TYRO3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Dtk in ELISAs and Western blots. In ELISAs and Western blots, no cross-reactivity or interference with recombinant mouse Dtk, recombinant human (rh) Axl, or rhMer is observed.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Protein S and Gas6 induce efferocytosis of HIV-1-infected cells.
Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.
Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow.
TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages.
Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
Chua BA, Ngo JA, Situ K, Ramirez CM, Nakano H, Morizono K
Virology 2018 Feb;515:176-190
Virology 2018 Feb;515:176-190
Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.
Kasikara C, Kumar S, Kimani S, Tsou WI, Geng K, Davra V, Sriram G, Devoe C, Nguyen KN, Antes A, Krantz A, Rymarczyk G, Wilczynski A, Empig C, Freimark B, Gray M, Schlunegger K, Hutchins J, Kotenko SV, Birge RB
Molecular cancer research : MCR 2017 Jun;15(6):753-764
Molecular cancer research : MCR 2017 Jun;15(6):753-764
Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow.
Yumoto K, Eber MR, Wang J, Cackowski FC, Decker AM, Lee E, Nobre AR, Aguirre-Ghiso JA, Jung Y, Taichman RS
Scientific reports 2016 Nov 7;6:36520
Scientific reports 2016 Nov 7;6:36520
TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages.
Zheng S, Hedl M, Abraham C
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 15;194(4):1928-37
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 15;194(4):1928-37
Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA
Journal of thrombosis and haemostasis : JTH 2005 Apr;3(4):733-41
Journal of thrombosis and haemostasis : JTH 2005 Apr;3(4):733-41
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Dtk in K562 Human Cell Line by Flow Cytometry. Detection of Dtk in K562 Human Cell Line by Flow Cytometry.
