TYRO3

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]

Description

TYRO3 protein tyrosine kinase

Protein family

Cancer-related genes, Enzymes, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

15:q15.1 (41557675 - 41583586)

Ensembl ID

ENSG00000092445  (ver. 84.38)

Orthologs

Mouse Tyro3: ENSMUSG00000027298

UniProt

Q06418

neXtProt

NX_Q06418

Human splice variants
Mouse splice variants