Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB12440 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12440, RRID:AB_10552593
- Product name
- EGLN1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of EGLN1.
- Storage
- Store at 4°C. Do not freeze.
Submitted references mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha.
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.
Dynamic HIF1A regulation during human placental development.
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Wong W, Goehring AS, Kapiloff MS, Langeberg LK, Scott JD
Science signaling 2008 Dec 23;1(51):ra18
Science signaling 2008 Dec 23;1(51):ra18
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.
Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D, Mancini C, Lazzaretti M, Mazzera L, Ravanetti L, Bonomini S, Ferrari L, Miranda C, Ladetto M, Neri TM, Neri A, Greco A, Mangoni M, Bonati A, Rizzoli V, Giuliani N
Blood 2007 Dec 15;110(13):4464-75
Blood 2007 Dec 15;110(13):4464-75
Dynamic HIF1A regulation during human placental development.
Ietta F, Wu Y, Winter J, Xu J, Wang J, Post M, Caniggia I
Biology of reproduction 2006 Jul;75(1):112-21
Biology of reproduction 2006 Jul;75(1):112-21
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL
Molecular cell 2005 Feb 18;17(4):503-12
Molecular cell 2005 Feb 18;17(4):503-12
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of EGLN1 using EGLN1 polyclonal antibody (Cat # PAB12440). Samples : Recombinant FLAG-His-EGLN2, EGLN1 and EGLN3 (10 ng/lane), HeLa whole cell lysate and MEF.