EGLN1

gene product
C1orf12, HIFPH2, PHD2, SM-20, ZMYND6
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009]
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647 antibodies from 34 providers.

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Novus Biologicals
140 antibodies
antibodies-online
205 antibodies
GeneTex
8 antibodies
Abnova Corporation
6 antibodies
Invitrogen Antibodies
9 antibodies
OriGene
10 antibodies
R&D Systems
10 antibodies
Proteintech Group
3 antibodies
LifeSpan BioSciences, Inc.
94 antibodies
Biorbyt
28 antibodies
NovoPro Bioscience Inc.
2 antibodies
Atlas Antibodies
1 antibody
HUABIO Research
1 antibody
Bioworld Technology, Inc
1 antibody
Acris Antibodies GmbH
2 antibodies
Affinity Biosciences
1 antibody
RabMAbs
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Boster Biological Technology
1 antibody
Creative Biolabs
14 antibodies
Aviva Systems Biology
5 antibodies
MyBioSource
7 antibodies
Abgent
2 antibodies
United States Biological
52 antibodies
St John's Laboratory
4 antibodies
Creative Diagnostics
4 antibodies
ProSci
2 antibodies
Bethyl Laboratories
1 antibody
Abbexa
9 antibodies
Sigma-Aldrich
2 antibodies
Leading Biology
1 antibody
EMD Millipore
1 antibody
GenWay
1 antibody