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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Product number
- ABIN152190 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Egl Nine Homolog 1 (C. Elegans) (EGLN1) antibody
- Antibody type
- Polyclonal
- Antigen
- The exact amino acid range is proprietary.General Immunogen area:NB 100-137 (LocusLink - 54583 Region - Internal)NB 100-138 (LocusLink - 54583 Region - c-terminus)NB 100-139 (LocusLink - 112399 Region - Internal)NB 100-295 (LocusLink - 54681 Region - c-terminus)NB 100-303 (LocusLink - 112399 Region - c-terminus)NB 100-310 (LocusLink - 111298 Region - c-terminus)ABIN250635 (mouse amino acid range 300-400).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 7 vials
- Storage
- Store at 4C. Do not freeze.
Submitted references A yeast two-hybrid system reconstituting substrate recognition of the von Hippel-Lindau tumor suppressor protein.
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.
Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia.
Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha.
AKAP12 regulates human blood-retinal barrier formation by downregulation of hypoxia-inducible factor-1alpha.
EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells.
Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.
Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system.
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.
Bex C, Knauth K, Dambacher S, Buchberger A
Nucleic acids research 2007;35(21):e142
Nucleic acids research 2007;35(21):e142
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.
Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D, Mancini C, Lazzaretti M, Mazzera L, Ravanetti L, Bonomini S, Ferrari L, Miranda C, Ladetto M, Neri TM, Neri A, Greco A, Mangoni M, Bonati A, Rizzoli V, Giuliani N
Blood 2007 Dec 15;110(13):4464-75
Blood 2007 Dec 15;110(13):4464-75
Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia.
Chang EI, Loh SA, Ceradini DJ, Chang EI, Lin SE, Bastidas N, Aarabi S, Chan DA, Freedman ML, Giaccia AJ, Gurtner GC
Circulation 2007 Dec 11;116(24):2818-29
Circulation 2007 Dec 11;116(24):2818-29
Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha.
Baek JH, Liu YV, McDonald KR, Wesley JB, Hubbi ME, Byun H, Semenza GL
The Journal of biological chemistry 2007 Aug 10;282(32):23572-80
The Journal of biological chemistry 2007 Aug 10;282(32):23572-80
AKAP12 regulates human blood-retinal barrier formation by downregulation of hypoxia-inducible factor-1alpha.
Choi YK, Kim JH, Kim WJ, Lee HY, Park JA, Lee SW, Yoon DK, Kim HH, Chung H, Yu YS, Kim KW
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Apr 18;27(16):4472-81
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Apr 18;27(16):4472-81
EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells.
Kondo S, Seo SY, Yoshizaki T, Wakisaka N, Furukawa M, Joab I, Jang KL, Pagano JS
Cancer research 2006 Oct 15;66(20):9870-7
Cancer research 2006 Oct 15;66(20):9870-7
Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.
McMahon S, Charbonneau M, Grandmont S, Richard DE, Dubois CM
The Journal of biological chemistry 2006 Aug 25;281(34):24171-81
The Journal of biological chemistry 2006 Aug 25;281(34):24171-81
Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system.
Stiehl DP, Wirthner R, Köditz J, Spielmann P, Camenisch G, Wenger RH
The Journal of biological chemistry 2006 Aug 18;281(33):23482-91
The Journal of biological chemistry 2006 Aug 18;281(33):23482-91
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.
Lu H, Dalgard CL, Mohyeldin A, McFate T, Tait AS, Verma A
The Journal of biological chemistry 2005 Dec 23;280(51):41928-39
The Journal of biological chemistry 2005 Dec 23;280(51):41928-39
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