BS4117

antibody from Bioworld Technology, Inc
Targeting: LIMK2
Provider product page for BS4117
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS4117 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS4117, RRID:AB_1663648
Product name
LIMK2 (phospho T505) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human LIMK2 around the phosphorylation site of Threonine 505.
Description
Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
LIMK2 protein structure - BS4117 shown in red.