Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362109 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362109, RRID:AB_10956381
- Product name
- anti-LIM Domain Kinase 2 (LIMK2) (pThr505) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr505 (R-Y-T (p) -V-V) derived from Human LIMK2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pThr505
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop.
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics.
Ohashi K, Nagata K, Maekawa M, Ishizaki T, Narumiya S, Mizuno K
The Journal of biological chemistry 2000 Feb 4;275(5):3577-82
The Journal of biological chemistry 2000 Feb 4;275(5):3577-82
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics.
Edwards DC, Sanders LC, Bokoch GM, Gill GN
Nature cell biology 1999 Sep;1(5):253-9
Nature cell biology 1999 Sep;1(5):253-9
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