TNFSF18

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]

Description

TNF superfamily member 18

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

1:q25.1 (173039960 - 173050963)

Ensembl ID

ENSG00000120337  (ver. 99.38)

Orthologs

Mouse Tnfsf18: ENSMUSG00000066755

UniProt

Q9UNG2

neXtProt

NX_Q9UNG2

Human splice variants
Mouse splice variants