Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 14754-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14754-1-AP, RRID:AB_2083706
- Product name
- COMT antibody
- Antibody type
- Polyclonal
- Description
- COMT antibody (Cat. #14754-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
Genetic Modulation of BET1L Confers Colorectal Cancer Susceptibility by Reducing miRNA Binding and m6A Modification.
Mechanistic analysis of erectile dysfunction in a depression rat model.
Entacapone alleviates acute kidney injury by inhibiting ferroptosis.
Vitamin D attenuated 6-OHDA-induced behavioural deficits, dopamine dysmetabolism, oxidative stress, and neuro-inflammation in mice.
Mechanism of Catechol-O-methyltransferase Regulating Orofacial Pain Induced by Tooth Movement.
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene.
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
Norepinephrine, active norepinephrine transporter, and norepinephrine-metabolism are involved in the generation of reactive oxygen species in human ovarian granulosa cells.
He Y, Li R, Yu Y, Huang C, Xu Z, Wang T, Chen M, Huang H, Qi Z
Neurochemistry international 2024 May;175:105700
Neurochemistry international 2024 May;175:105700
Genetic Modulation of BET1L Confers Colorectal Cancer Susceptibility by Reducing miRNA Binding and m6A Modification.
Li S, Du M, Xu K, Ben S, Zhu T, Guo M, Xin J, Zhu L, Gu D, Zhang Z, Wang M
Cancer research 2023 Jul 5;83(13):2142-2154
Cancer research 2023 Jul 5;83(13):2142-2154
Mechanistic analysis of erectile dysfunction in a depression rat model.
Hong ZM, Chen ZL, Feng JL, Wang SJ, Qiu JF, Zeng YL, Wang Q, Wang JS
The Journal of international medical research 2022 May;50(5):3000605221100334
The Journal of international medical research 2022 May;50(5):3000605221100334
Entacapone alleviates acute kidney injury by inhibiting ferroptosis.
Yang J, Sun X, Huang N, Li P, He J, Jiang L, Zhang X, Han S, Xin H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22399
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jul;36(7):e22399
Vitamin D attenuated 6-OHDA-induced behavioural deficits, dopamine dysmetabolism, oxidative stress, and neuro-inflammation in mice.
Bayo-Olugbami A, Nafiu AB, Amin A, Ogundele OM, Lee CC, Owoyele BV
Nutritional neuroscience 2022 Apr;25(4):823-834
Nutritional neuroscience 2022 Apr;25(4):823-834
Mechanism of Catechol-O-methyltransferase Regulating Orofacial Pain Induced by Tooth Movement.
Zhou Y, Song Z, Chen S, Yao F, Liu J, Ouyang Z, Liao Z
BioMed research international 2021;2021:4229491
BioMed research international 2021;2021:4229491
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Guo Y, Zhu X, Zeng M, Qi L, Tang X, Wang D, Zhang M, Xie Y, Li H, Yang X, Chen D
Translational psychiatry 2021 May 27;11(1):328
Translational psychiatry 2021 May 27;11(1):328
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274
Aging 2021 Mar 26;13(7):10240-10274
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene.
Liu Z, Luo X, Liu L, Zhao W, Guo S, Guo Y, Wang N, He H, Liao X, Ma W, Zhou H, Zhang T
Acta biochimica et biophysica Sinica 2013 Dec;45(12):1002-10
Acta biochimica et biophysica Sinica 2013 Dec;45(12):1002-10
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S
Journal of proteomics 2013 Apr 26;82:193-229
Journal of proteomics 2013 Apr 26;82:193-229
Norepinephrine, active norepinephrine transporter, and norepinephrine-metabolism are involved in the generation of reactive oxygen species in human ovarian granulosa cells.
Saller S, Merz-Lange J, Raffael S, Hecht S, Pavlik R, Thaler C, Berg D, Berg U, Kunz L, Mayerhofer A
Endocrinology 2012 Mar;153(3):1472-83
Endocrinology 2012 Mar;153(3):1472-83
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 14754-1-AP(COMT antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using COMT antibody 14754-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 14754-1-AP(COMT antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 14754-1-AP(COMT antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The COMT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human COMT. This antibody recognizes human,mouse,rat antigen. The COMT antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.