COMT

gene product
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
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634 antibodies from 39 providers.

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Antibody
Proteintech Group
1 antibody
antibodies-online
183 antibodies
NovoPro Bioscience Inc.
9 antibodies
Novus Biologicals
9 antibodies
GeneTex
6 antibodies
LifeSpan BioSciences, Inc.
133 antibodies
NSJ Bioreagents
5 antibodies
Abnova Corporation
12 antibodies
Biorbyt
23 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
14 antibodies
Acris Antibodies GmbH
11 antibodies
St John's Laboratory
5 antibodies
Antibodies.com
3 antibodies
Boster Biological Technology
3 antibodies
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
Cell Signaling Technology, Inc
1 antibody
Aviva Systems Biology
5 antibodies
Everest Biotech
2 antibodies
Bioworld Technology, Inc
2 antibodies
Creative Biolabs
36 antibodies
Abgent
7 antibodies
Creative Diagnostics
10 antibodies
HUABIO Research
1 antibody
Arigo
3 antibodies
OriGene
11 antibodies
RabMAbs
5 antibodies
MyBioSource
7 antibodies
ProSci
5 antibodies
R&D Systems
1 antibody
United States Biological
68 antibodies
Abbexa
9 antibodies
RayBiotech, Inc.
8 antibodies
Leading Biology
8 antibodies
Sigma-Aldrich
6 antibodies
EMD Millipore
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody