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- Antigen structure
- References [7]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- ABIN388586 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 666-699), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 666-699, C-Term
- Antibody clone number
- RB10849
- Vial size
- 400 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression.
Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner.
Rubicon controls endosome maturation as a Rab7 effector.
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells.
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.
Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability.
Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus.
Sun Q, Zhang J, Fan W, Wong KN, Ding X, Chen S, Zhong Q
The Journal of biological chemistry 2011 Jan 7;286(1):185-91
The Journal of biological chemistry 2011 Jan 7;286(1):185-91
Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner.
Neely KM, Green KN, LaFerla FM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Feb 23;31(8):2781-91
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Feb 23;31(8):2781-91
Rubicon controls endosome maturation as a Rab7 effector.
Sun Q, Westphal W, Wong KN, Tan I, Zhong Q
Proceedings of the National Academy of Sciences of the United States of America 2010 Nov 9;107(45):19338-43
Proceedings of the National Academy of Sciences of the United States of America 2010 Nov 9;107(45):19338-43
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells.
Han J, Hou W, Goldstein LA, Lu C, Stolz DB, Yin XM, Rabinowich H
The Journal of biological chemistry 2008 Jul 11;283(28):19665-77
The Journal of biological chemistry 2008 Jul 11;283(28):19665-77
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.
Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, Jung JU
Nature cell biology 2006 Jul;8(7):688-99
Nature cell biology 2006 Jul;8(7):688-99
Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability.
Ionov Y, Nowak N, Perucho M, Markowitz S, Cowell JK
Oncogene 2004 Jan 22;23(3):639-45
Oncogene 2004 Jan 22;23(3):639-45
Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus.
Perelman B, Dafni N, Naiman T, Eli D, Yaakov M, Feng TL, Sinha S, Weber G, Khodaei S, Sancar A, Dotan I, Canaani D
Genomics 1997 May 1;41(3):397-405
Genomics 1997 May 1;41(3):397-405
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
