DCABH-6469

antibody from Creative Diagnostics

Targeting: SLC1A2 EAAT2, GLT-1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

DCABH-6469

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-6469, RRID:AB_2479923

Product name

Rabbit Anti-Human GLT-1 monoclonal antibody, clone 0I0M28

Antibody type

Monoclonal

Description

Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

0I0M28

Concentration

0.5 mg/ml

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.