BS6523

antibody from Bioworld Technology, Inc
Targeting: ANG RAA1, RNASE5
Provider product page for BS6523
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6523 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ANG polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ANG.
Description
Angiogenesis is defined as the process of neovascularization and formation of new blood vessels from the established micro-circulation. Angiogenin (ANG or ANG I) is a non-glycosylated polypeptide, 123 amino acids in length, whose function is central to this process. ANG I shows a high degree of homology with known ribonucleases such as pancreatic ribonuclease A, and the capacity of ANG I to induce blood vessel growth is critically dependent on its ribonucleolytic activity. ANG I is thought to be involved in the development of solid tumors, and ANG I antagonists are capable of inhibiting tumor growth. By a poorly understood mechanism, ANG I is endocytosed by subconfluent endothelial cells and translocated to the nucleus where it accumulates in the nucleolus. The ANG I receptor has not yet been identified.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ANG protein structure - BS6523 shown in red.