NEIL2

gene product
FLJ31644, MGC2832, MGC4505, NEH2
This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified. [provided by RefSeq, Mar 2017]
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antibodies-online
46 antibodies
Novus Biologicals
5 antibodies
LifeSpan BioSciences, Inc.
25 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
5 antibodies
Atlas Antibodies
3 antibodies
Invitrogen Antibodies
6 antibodies
OriGene
1 antibody
Abgent
2 antibodies
GeneTex
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Acris Antibodies GmbH
3 antibodies
Biorbyt
8 antibodies
Aviva Systems Biology
2 antibodies
Bioworld Technology, Inc
1 antibody
Creative Biolabs
5 antibodies
Creative Diagnostics
3 antibodies
MyBioSource
3 antibodies
St John's Laboratory
1 antibody
United States Biological
14 antibodies
ProSci
1 antibody
Sigma-Aldrich
1 antibody