ABIN350137
antibody from antibodies-online
Targeting: CACNA1C
CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN350137 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350137, RRID:AB_10781932
- Product name
- anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 50-100) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from aa region 50-100 of human CACNA1C conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 96% identity with mouse, rat and rabbit sequence.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 50-100
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Ca2+ channel sensitivity towards the blocker isradipine is affected by alternative splicing of the human alpha1C subunit gene.
Different voltage-dependent inhibition by dihydropyridines of human Ca2+ channel splice variants.
Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart.
Zühlke RD, Bouron A, Soldatov NM, Reuter H
FEBS letters 1998 May 8;427(2):220-4
FEBS letters 1998 May 8;427(2):220-4
Different voltage-dependent inhibition by dihydropyridines of human Ca2+ channel splice variants.
Soldatov NM, Bouron A, Reuter H
The Journal of biological chemistry 1995 May 5;270(18):10540-3
The Journal of biological chemistry 1995 May 5;270(18):10540-3
Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart.
Schultz D, Mikala G, Yatani A, Engle DB, Iles DE, Segers B, Sinke RJ, Weghuis DO, Klöckner U, Wakamori M
Proceedings of the National Academy of Sciences of the United States of America 1993 Jul 1;90(13):6228-32
Proceedings of the National Academy of Sciences of the United States of America 1993 Jul 1;90(13):6228-32
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